Skip to search formSkip to main contentSkip to account menu

SDHB gene

Known as: SDH2, HOMOLOG OF, iron-sulfur subunit of complex II, SUCCINATE DEHYDROGENASE 2, S. CEREVISIAE, HOMOLOG OF 
This gene plays a role in electron transport in the mitochondria.
National Institutes of Health

Related topics

Related topics

5 relations
Cell RespirationHereditary ParagangliomaHereditary Paraganglioma-Pheochromocytoma SyndromeOxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.
BACKGROUND Mutations in the Fe-S cluster-containing SDHB subunit of succinate dehydrogenase cause familial cancer syndromes… 
2016
2016
Down-regulation of succinate dehydrogenase subunit B and up-regulation of pyruvate dehydrogenase kinase 1 predicts poor prognosis in recurrent nasopharyngeal carcinoma
Succinate dehydrogenase subunit B (SDHB) and pyruvate dehydrogenase kinase 1 (PDK1) play key roles in the regulation of growth… 
2014
2014
Phenotype of SDHB mutation carriers in the Netherlands
SDHB mutation carriers are predisposed to developing paragangliomas (PGLs). The objective of this study was to assess genotype… 
2012
2012
Somatic Mutation Analysis of the SDHB, SDHC, SDHD, and RET Genes in the Clinical Assessment of Sporadic and Hereditary Pheochromocytoma
Systemic analysis of somatic mutations of other susceptibility genes in syndromic tumors as well as apparently sporadic tumors in… 
2010
2010
A large deletion in the succinate dehydrogenase B gene (SDHB) in a Japanese patient with abdominal paraganglioma and concomitant metastasis.
Recently, mutations in nuclear genes encoding two mitochondrial complex II subunit proteins, Succinate dehydrogenase D (SDHD) and… 
2010
2010
Germinal mutations of RET, SDHB, SDHD, and VHL genes in patients with apparently sporadic pheochromocytomas and paragangliomas.
INTRODUCTION Pheochromocytomas and paragangliomas are derived from neural crest cells and are localized mainly in adrenal medulla… 
2010
2010
Mutation analysis of the SDHB and SDHD genes in pheochromocytomas and paragangliomas: identification of a novel nonsense mutation (Q168X) in the SDHB gene.
Pheochromocytoma (PCC) and paraganglioma (PGL) are tumors of the autonomic nervous system. The former is a tumor that occurs in… 
2009
2009
Ischemic Stroke and Rhabdomyolysis in a 15 Year-old Girl with Paraganglioma due to an SDHB Exon 6 (Q214X) Mutation
BACKGROUND We report a 15-year-old girl with a recent diagnosis of type 2 diabetes mellitus who presented in malignant… 
Review
2006
Review
2006
The Occurrence of SDHB Gene Mutations in Pheochromocytoma
Abstract:  Pheochromocytomas (PCCs) are rare tumors arising from neural crest–derived chromaffin cells. The majority of these… 
2005
2005
There is no evidence that the SDHB gene is involved in neuroblastoma development.
Neuroblastoma and pheochromocytoma have the same embryonal origin. They originate from neural crest cells, and they usually… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)