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SD-208

National Institutes of Health

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Pteridines

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2015
2015
Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase
Invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) are the most frequently occurring histological subtypes of… 
2015
2015
AWARD NUMBER: W81XWH-13-1-0163 TITLE: Novel Therapeutic Targets to Inhibit Tumor Microenvironment-Induced Castration-Resistant Prostate Cancer
AR signaling is essential for the growth and survival of prostate cancer (PCa), including most of the lethal castration-resistant… 
2015
2015
SD-208 inhibited prostate cancer cells proliferation, survival, and invasion and the anti-proliferative effect of SD-208 was mediated through the inhibition of PKD.
2008
2008
Attenuated Transforming Growth Factor Beta Signaling as a Therapeutic for Prostate Cancer Progression
Abstract : The purpose or this proposal is to determine the effects of stromal TGF-beta signaling inhibition by SD-208 (a TbetaRI… 
2004
2004
In vivo and In vitro Cells Enhances Immunogenicity of Murine and Human Glioma Kinase Inhibitor , Inhibits Growth and Invasiveness and Receptor I β SD-208 , a Novel Transforming Growth Factor
The cytokine transforming growth factor (TGF), by virtue of its immunosuppressive and promigratory properties, has become a major…