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SCUBE2 gene

Known as: Signal Peptide, CUB Domain, EGF-Like 2 Gene, SIGNAL PEPTIDE-, CUB DOMAIN-, AND EGF-LIKE DOMAINS-CONTAINING PROTEIN 2, FLJ16792 
This gene may be involved in both cell proliferation and cell-cell adhesion.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
SCUBE2, vascular endothelium, and vascular complications: A systematic review.
  • Hirowati Ali
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 2020
  • Corpus ID: 215741777
Highly Cited
2019
Highly Cited
2019
The Inhibitory Effect of (−)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing SCUBE2 Methylation and DNMT Activity
Epigenetic modifications are important mechanisms responsible for cancer progression. Accumulating data suggest that… 
2018
2018
Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis
Objective— SCUBE2 (signal peptide-CUB-EGF domain-containing protein 2), expressed on the endothelial cell surface, functions as a… 
2018
2018
Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial‐to‐mesenchymal transition
2018
2018
Integrated clinical and omics approach to rare diseases: novel genes and oligogenic inheritance in holoprosencephaly
Holoprosencephaly is a pathology of forebrain development characterized by high phenotypic heterogeneity. The disease presents… 
2017
2017
Overexpression of SCUBE2 Inhibits Proliferation, Migration, and Invasion in Glioma Cells
Signal peptide CUB EGF-like domain-containing protein 2 (SCUBE2), a member of the SCUBE family of proteins, was recently found to… 
2015
2015
Decreased expression of SCUBE2 is associated with progression and prognosis in colorectal cancer.
Signal peptide-CUB-epidermal growth factor-like domain-containing protein 2 (SCUBE2), a member of the SCUBE protein family, is a… 
2013
2013
Localization and characterization of a novel secreted protein, SCUBE2, in the development and progression of atherosclerosis.
Inhibition of atherosclerosis progression has long been the subject of intensive pathophysiologic investigations. The… 
2012
2012
Co-expression of genes with estrogen receptor-α and progesterone receptor in human breast carcinoma tissue
Abstract Background: To detect genes associated with the expression of ESR1 and PGR – as well as of their protein products… 
2009
2009
Isolation and characterization of a secreted , cell-surface glycoprotein SCUBE 2 from humans
Ming-Tzu TSAI*†1, Chien-Jui CHENG‡1, Yuh-Charn LIN*, Chun-Chuan CHEN*, Ann-Ru WU*, Min-Tzu WU*, Cheng-Chin HSU† and Ruey-Bing… 
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