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SCN5A gene

Known as: PFHB1, LQT3, SCN5A 
National Institutes of Health

Related topics

Related topics

4 relations
Hereditary bundle branch system defectLONG QT SYNDROME 3SCN7A geneSICK SINUS SYNDROME 1, AUTOSOMAL RECESSIVE

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Structure-based assessment of disease-related mutations in human voltage-gated sodium channels
Voltage-gated sodium (Nav) channels are essential for the rapid upstroke of action potentials and the propagation of electrical… 
Highly Cited
2012
Highly Cited
2012
High Prevalence of Long QT Syndrome–Associated SCN5A Variants in Patients With Early-Onset Lone Atrial Fibrillation
Background—Atrial fibrillation (AF) is the most common cardiac arrhythmia. The cardiac sodium channel, NaV1.5, plays a pivotal… 
Highly Cited
2010
Highly Cited
2010
Calibration free laser-induced breakdown spectroscopy of oxide materials
Highly Cited
2007
Highly Cited
2007
The effects of tumble and swirl flows on flame propagation in a four-valve S.I. engine
Highly Cited
2005
Highly Cited
2005
Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population
The QT interval (QT) reflects cardiac ventricular repolarization and varies according to various known factors such as heart rate… 
Highly Cited
2004
Highly Cited
2004
Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients
Administration of specific drugs may occasionally induce acquired long QT syndrome (aLQTS), a disorder that predisposes to… 
Highly Cited
2003
Highly Cited
2003
A Ubiquitous Splice Variant and a Common Polymorphism Affect Heterologous Expression of Recombinant Human SCN5A Heart Sodium Channels
Abstract— Amino acid sequence variations in SCN5A are known to affect function of wild-type channels and also those with… 
Highly Cited
2001
Highly Cited
2001
The sodium channel β‐subunit SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart
1 Cardiac sodium channels are composed of a pore‐forming α‐subunit, SCN5a, and one or more auxiliary β‐subunits. The aim of this… 
Highly Cited
2000
Highly Cited
2000
Diagnostics and modeling of a macroscopic plasma display panel cell
A macroscopic plasma display discharge cell has been designed in order to more easily study the plasma evolution in dielectric… 
Highly Cited
1996
Highly Cited
1996
Genomic organization of the human SCN5A gene encoding the cardiac sodium channel.
The voltage-gated cardiac sodium channel, SCN5A, is responsible for the initial upstroke of the action potential. Mutations in… 
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