SCID-Repopulating Cell

Known as: SRC, SCID Repopulating Cell, Severe Combined Immunodeficient Repopulating Cell 
A human hematopoietic stem cell that is able to repopulate the hematopoietic system of non-obese diabetic/severe combined immunodeficient mice (NOD… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Improving approaches for hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) mobilization is clinically… (More)
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Highly Cited
2005
Highly Cited
2005
The nonobese diabetic/severe combined immune deficiency (NOD/SCID) xenotransplantation model has emerged as a widely used assay… (More)
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Highly Cited
2003
Highly Cited
2003
It has been proposed that bone marrow (BM) hematopoietic stem and progenitor cells are distributed along an oxygen (O2) gradient… (More)
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Highly Cited
2003
Highly Cited
2003
Precise analysis of human CD34-negative (CD34(-)) hematopoietic stem cells (HSCs) has been hindered by the lack of a simple and… (More)
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Highly Cited
2003
Highly Cited
2003
Efficient vector transduction of hematopoietic stem cells is a requirement for successful gene therapy of hematologic disorders… (More)
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Highly Cited
2003
Highly Cited
2003
A major problem hampering effective stem cell–based therapies is the absence of a clear understanding of the human hematopoietic… (More)
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Highly Cited
2002
Highly Cited
2002
To measure the ability of human hematopoietic stem cells (HSCs), the SCID-repopulating cell (SRC) assay has been widely used… (More)
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Highly Cited
1997
Highly Cited
1997
The purification of primitive human hematopoietic stem cells has been impaired by the absence of repopulation assays. By using a… (More)
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Highly Cited
1997
Highly Cited
1997
We have previously reported the development of in vivo functional assays for primitive human hematopoietic cells based on their… (More)
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Highly Cited
1996
Highly Cited
1996
The development of stem–cell gene therapy is hindered by the absence of repopulation assays for primitive human hematopoietic… (More)
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