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SCH-530348
Known as:
SCH 530348
, SCH530348
National Institutes of Health
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vorapaxar
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Review
2018
Review
2018
The PAR 1 antagonist , SCH 79797 , alters platelet morphology and function indepen-dently of PARs
Hannah Lee
,
R. Hamilton
2018
Corpus ID: 4137502
doi:10.1160/TH12-06-0389 Thromb Haemost 2013; 109: 164–167 Dear Sirs, Protease-activated receptors (PARs) are a family of four G…
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2015
2015
Bacterial Pulmonary Infection Proteinase-Activated Receptor 1 during Regulation of Neutrophilic Inflammation by Chambers
R. José
,
A. Williams
,
P. Mercer
,
M. Sulikowski
,
Jeremy S. Brown
,
R. Chambers
2015
Corpus ID: 1942840
Neutrophils are key effector cells of the innate immune response to pathogenic bacteria, but excessive neutrophilic inflammation…
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Review
2012
Review
2012
Protease-Activated Receptor-1 Antagonists: Focus on SCH 530348
J. Sugunaraj
,
V. Mehta
,
A. Kalra
,
R. Sukhija
,
C. Palaniswamy
American Journal of Therapeutics
2012
Corpus ID: 31946571
Currently available antiplatelet agents have shown improved short- and long-term clinical outcomes but are associated with…
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Review
2010
Review
2010
Thrombin receptor antagonism –the potential of antiplatelet medication SCH 530348
Tracy E. Macaulay
,
Christopher Allen
,
K. Ziada
Expert Opinion on Pharmacotherapy
2010
Corpus ID: 25483032
Importance of the field: Coronary artery disease is a leading cause of morbidity and mortality worldwide. Platelet activation and…
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Review
2010
Review
2010
Inhibiting PAR-1 in the prevention and treatment of atherothrombotic events
S. D. Tomasello
,
D. Angiolillo
,
S. Goto
Expert Opinion on Investigational Drugs
2010
Corpus ID: 37201477
Importance of the field: Aspirin, an irreversible inhibitor of thromboxane A2 production, in combination with clopidogrel, an…
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2010
2010
[Update on new antithrombotic treatments].
F. Boehlen
,
Y. Tirefort-Dimitrova
,
P. de Moerloose
,
P. Fontana
Revue medicale suisse
2010
Corpus ID: 23237066
Update on new antithrombotic treatments Antithrombotic treatments are frequently prescribed in different clinical situations…
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2009
2009
Convergent Synthesis of Both Enantiomers of 4-Hydroxypent-2- ynoic Acid Diphenylamide for a Thrombin Receptor Antagonist Sch 530348 and Himbacine Analogues
A. Zaks
,
Maria M. Tamarez
,
Tao Li
2009
Corpus ID: 62835960
Sch 530348 and many himbacine analogues were prepared by using 4-hydroxypent-2-ynoic acid diphenylamide as the only chiral…
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Review
2009
Review
2009
New antiplatelet agents.
G. Spectre
,
D. Varon
Current opinion in hematology
2009
Corpus ID: 11271945
PURPOSE OF REVIEW Cardiovascular events are still a major concern despite dual antiplatelet treatment with aspirin and…
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2009
2009
Improving antiplatelet therapy for atherothrombotic disease
Hildemann Sk
,
C. Bode
Hämostaseologie
2009
Corpus ID: 44996874
Summary Morbidity and mortality in patients with atherothrombotic disease remain high despite the use of antiplatelet therapy…
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Review
2008
Review
2008
Future prospects in anti-platelet therapy: a review of potential P2Y12 and thrombin receptor antagonists.
Nicholas B. Norgard
,
Mazen Abu-Fadel
Recent Advances in Cardiovascular Drug Discovery…
2008
Corpus ID: 11201052
Atherothrombosis is an acute complication that develops on the surface of a ruptured atheromatous plaque or as a consequence of…
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