Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

SCH 48461

Known as: SCH-48461 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Beta-lactam cholesterol absorption inhibitors.
beta-Lactams have recently been identified as potent, highly efficacious cholesterol absorption inhibitors (CAIs). The discovery… Expand
Is this relevant?
2004
2004
Effect of a New b-Sitosterol Analogue on Plasma Lipid Concentrations in Rats 1 )
disease (CHD) or atherosclerosis is elevated levels of serum cholesterol. Recent clinical trials and studies have confirmed that… Expand
  • figure 2
  • figure 3
  • figure 4
  • figure 1
  • figure 5
Is this relevant?
2002
2002
Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte Published, JLR Papers in Press…
Intestinal cholesterol absorption is a major determinant of plasma low density lipoprotein-cholesterol (LDL-C) concentrations… Expand
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2001
2001
The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
Ezetimibe (SCH 58235) and SCH 48461 are potent cholesterol absorption inhibitors, which cause significant decreases in plasma… Expand
Is this relevant?
2001
2001
Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study.
SCH 48461, an inhibitor of gastrointestinal absorption of cholesterol, was evaluated for its effects on lipid parameters in… Expand
Is this relevant?
1998
1998
Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
(3R)-(3-Phenylpropyl)-1,(4S)-bis(4-methoxyphenyl)-2-azetidinone (2, SCH 48461), a novel inhibitor of intestinal cholesterol… Expand
Is this relevant?
1997
1997
Spectroscopic identification of an amorphous-to-crystalline drug transition in a solid dispersion SCH 48461 capsule formulation.
Changes in the dissolution of a solid dispersion capsule formulation composed of amorphous SCH 48461 in a polyethylene glycol… Expand
Is this relevant?
1996
1996
2-Azetidinone cholesterol absorption inhibitors: structure-activity relationships on the heterocyclic nucleus.
A series of azetidinone cholesterol absorption inhibitors related to SCH 48461 ((-)-6) has been prepared, and compounds were… Expand
Is this relevant?
1995
1995
Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461.
The amount of cholesterol that circulates in the plasma as lipoproteins can be affected by the balance of cholesterol metabolism… Expand
Is this relevant?
1994
1994
SCH 48461, a novel inhibitor of cholesterol absorption
 
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE