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SCH 48461

Known as: SCH-48461 
National Institutes of Health

Papers overview

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Review
2004
Review
2004
Beta-lactam cholesterol absorption inhibitors.
beta-Lactams have recently been identified as potent, highly efficacious cholesterol absorption inhibitors (CAIs). The discovery… 
2004
2004
Effect of a New b-Sitosterol Analogue on Plasma Lipid Concentrations in Rats 1 )
disease (CHD) or atherosclerosis is elevated levels of serum cholesterol. Recent clinical trials and studies have confirmed that… 
Review
2003
Review
2003
Ezetimibe for Management of Hypercholesterolemia
OBJECTIVE: To review the primary literature describing the pharmacology of ezetimibe and clinical trials investigating its use in… 
Highly Cited
2002
Highly Cited
2002
Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte Published, JLR Papers in Press…
Intestinal cholesterol absorption is a major determinant of plasma low density lipoprotein-cholesterol (LDL-C) concentrations… 
2002
2002
Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors.
2001
2001
Reduction of LDL Cholesterol in Patients with Primary Hypercholesterolemia by SCH 48461: Results of a Multicenter Dose‐Ranging Study
SCH 48461, an inhibitor of gastrointestinal absorption of cholesterol, was evaluated for its effects on lipid parameters in… 
1998
1998
Sugar-substituted 2-azetidinones as cholesterol absorption inhibitors.
1997
1997
Spectroscopic identification of an amorphous-to-crystalline drug transition in a solid dispersion SCH 48461 capsule formulation.
1996
1996
Effect of SCH 48461 on oral cholesterol absorption
Clinical Pharmacology & Therapeutics (1996) 59, 194–194; doi: 10.1038/sj.clpt.1996.274 
1994
1994
SCH 48461, a novel inhibitor of cholesterol absorption
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