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SC 58125

Known as: SC-58125, SC58125 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice.
Highly Cited
2003
Highly Cited
2003
The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis.
PURPOSE We investigated the potential of cyclooxygenase (COX)-2 as anappropriate chemopreventive and/or therapeutic target for… 
Highly Cited
2002
Highly Cited
2002
Radiosynthesis, in vitro validation, and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors.
UNLABELLED In this article, we describe the radiosynthesis and evaluation of 18F-labeled cyclooxygenase (COX) inhibitors. 18F… 
Highly Cited
2000
Highly Cited
2000
Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells.
Highly Cited
1999
Highly Cited
1999
Hyperalgesia due to nerve injury: role of prostaglandins
Highly Cited
1997
Highly Cited
1997
A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells.
Highly Cited
1997
Highly Cited
1997
Differential inhibition of human prostaglandin endoperoxide synthase-1 and -2 by nonsteroidal anti-inflammatory drugs.
We have evaluated the selectivity in vitro of various conventional nonsteroidal anti-inflammatory drugs (NSAIDs) and new anti… 
Highly Cited
1997
Highly Cited
1997
The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia
Highly Cited
1996
Highly Cited
1996
Cyclooxygenases-1 and −2 of Endothelial Cells Utilize Exogenous or Endogenous Arachidonic Acid for Transcellular Production of Thromboxane (*)
The presence of prostaglandin (PG) H in the supernatant of human umbilical vein endothelial cells (HUVEC) stimulated by thrombin… 
Highly Cited
1996
Highly Cited
1996
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.
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