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SC 51089

Known as: Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-(1-oxo-3-(4-pyridinyl)propyl)hydrazide, monohydrochloride, SC-51089, SC51089 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

HydrazinesOxazepines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice
2011
2011
Function of prostaglandin E2 EP receptors in the acute outcome of rodent hypoxic ischemic encephalopathy
2010
2010
Targeting the prostaglandin E2 EP1 receptor and cyclooxygenase-2 in the amygdala kindling model in mice
2010
2010
Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia.
2000
2000
The prostaglandin E series modulates high-voltage-activated calcium channels probably through the EP3 receptor in rat paratracheal ganglia
1999
1999
Responses of intraocular pressure and the pupil of feline eyes to prostaglandin EP1 and FP receptor agonists.
PURPOSE Previous studies suggested that FP receptors do not mediate the relaxation of the ciliary muscle and reduction of… 
1998
1998
Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost.
Highly Cited
1996
Highly Cited
1996
Aminoacetyl moiety as a potential surrogate for diacylhydrazine group of SC-51089, a potent PGE2 antagonist, and its analogs.
8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, monohydrochloride (1, SC… 
Highly Cited
1994
Highly Cited
1994
Antinociceptive effect of spinally delivered prostaglandin E receptor antagonists in the formalin test on the rat
1994
1994
Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures.
1. The metabolism of SC-42867 and SC-51089, two PGE2 antagonists, was studied in cultured rat and human hepatocytes. Both… 
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