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SC 51089

Known as: Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-(1-oxo-3-(4-pyridinyl)propyl)hydrazide, monohydrochloride, SC-51089, SC51089 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
  • Xiaochun Zhao, Tao Wu, +9 authors Jian Wang
  • Brain, Behavior, and Immunity
  • 2015
  • Corpus ID: 25803527
Inflammatory mechanisms mediated by prostaglandins may contribute to the progression of intracerebral hemorrhage (ICH)-induced… Expand
2013
2013
Cyclooxygenase-2-derived prostaglandin E2 (PGE2) contributes to excitotoxic and ischemic neuronal cell death by engaging neuronal… Expand
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2010
2010
Disruption of the blood-brain barrier (BBB) after cerebral ischemia is considered to be the initial step in the development of… Expand
Highly Cited
2009
Highly Cited
2009
We investigated the preclinical characteristics of the neuroprotective effect of the prostaglandin E2 type 1 receptor (EP1… Expand
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2008
2008
The prostanoid synthesizing enzyme cyclooxygenase-2 (COX-2) is involved in the mechanisms of cerebral ischemia, an effect… Expand
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Highly Cited
2002
Highly Cited
2002
Anandamide can be metabolized by cyclooxygenase-2 to produce prostaglandin E(2) (PGE(2)) ethanolamide. The purpose of this study… Expand
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2001
2001
8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, monohydrochloride (1, SC… Expand
1999
1999
PURPOSE Previous studies suggested that FP receptors do not mediate the relaxation of the ciliary muscle and reduction of… Expand
Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS Receptors activated by prostaglandin (PG) E2 are pharmacologically subdivided into four subtypes (EP1-EP4). The… Expand
Highly Cited
1996
Highly Cited
1996
8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, monohydrochloride (1, SC… Expand