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SC 45647

Known as: SC-45647, SC45647 
National Institutes of Health

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1 relation

Broader (1)

Guanidines

Papers overview

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Highly Cited
2015
Highly Cited
2015
Postsynaptic P2X3‐containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice
Acute inhibition of purinergic receptors with a selective P2X3 antagonist prevents transmission of information from taste buds to… 
2015
2015
Mice Lacking Pannexin 1 Release ATP and Respond Normally to All Taste Qualities.
Adenosine triphosphate (ATP) is required for the transmission of all taste qualities from taste cells to afferent nerve fibers… 
2010
2010
Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate.
Regulation of the putative amiloride and benzamil (Bz)-insensitive TRPV1t salt taste receptor by phosphatidylinositol 4,5… 
Highly Cited
2008
Highly Cited
2008
Norepinephrine Is Coreleased with Serotonin in Mouse Taste Buds
ATP and serotonin (5-HT) are neurotransmitters secreted from taste bud receptor (type II) and presynaptic (type III) cells… 
2008
2008
Consumption of SC45647 and sucralose by rats selectively bred for high and low saccharin intake.
Mammals' affinity for sweet tastes exists alongside dramatic variation among species and individuals in responses to sweeteners… 
Highly Cited
2004
Highly Cited
2004
Umami taste responses are mediated by alpha-transducin and alpha-gustducin.
The sense of taste comprises at least five distinct qualities: sweet, bitter, sour, salty, and umami, the taste of glutamate. For… 
2004
2004
Monosodium glutamate and sweet taste: discrimination between the tastes of sweet stimuli and glutamate in rats.
Generalization of a conditioned taste aversion (CTA) is based on similarities in taste qualities shared by the aversive substance… 
Highly Cited
2004
Highly Cited
2004
Allelic Variation of the Tas1r3 Taste Receptor Gene Selectively Affects Behavioral and Neural Taste Responses to Sweeteners in the F2 Hybrids between C57BL/6ByJ and 129P3/J Mice
Recent studies have shown that the T1R3 receptor protein encoded by the Tas1r3 gene is involved in transduction of sweet taste… 
Highly Cited
2002
Highly Cited
2002
Partial Rescue of Taste Responses of α-Gustducin Null Mice by Transgenic Expression of α-Transducin
The transduction of responses to bitter and sweet compounds utilizes guanine nucleotide binding proteins (G proteins) and their… 
1998
1998
The Relationship Between Intravenous Cocaine Self-Administration and Avidity for Saccharin
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