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SC 435

Known as: SC-435, SC435 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Deficiency of multidrug resistance 2 (mdr2), a canalicular phospholipid floppase, leads to excretion of low‐phospholipid “toxic… Expand
2011
2011
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of premature infants, but its etiology remains… Expand
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Highly Cited
2010
Highly Cited
2010
Bile acid sequestrants have been shown to lower glucose levels in patients with type 2 diabetes. To investigate how colesevelam… Expand
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2008
2008
SR-BI/apoE double knockout (dKO) mice exhibit many features of human coronary heart disease (CHD), including hypercholesterolemia… Expand
2005
2005
We have demonstrated that SC-435, an apical sodium codependent bile acid transporter (ASBT) inhibitor, lowers plasma low-density… Expand
Highly Cited
2005
Highly Cited
2005
  • Hai Li, Frank Chen, +8 authors G. Xu
  • American journal of physiology. Gastrointestinal…
  • 2005
  • Corpus ID: 16134395
The regulation of the rabbit apical sodium-dependent bile acid transporter (ASBT) was studied both in vivo and in vitro. New… Expand
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Highly Cited
2004
Highly Cited
2004
  • H. Li, G. Xu, +7 authors G. Salen
  • Metabolism: clinical and experimental
  • 2004
  • Corpus ID: 42736469
We investigated the effect of SC-435, a competitive inhibitor of ileal apical sodium-dependent bile acid cotransporter (ASBT) on… Expand
Highly Cited
2003
Highly Cited
2003
Blocking intestinal bile acid absorption by inhibiting the apical sodium codependent bile acid transporter (ASBT) is a target for… Expand
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2002
2002
Male Hartley guinea pigs (10/group) were assigned either to a control diet (no drug treatment) or to diets containing 0.4, 2.2… Expand
Highly Cited
2002
Highly Cited
2002
Objective—Cloning of the ileal apical sodium-dependent bile acid transporter (ASBT) has identified a new pharmacological target… Expand
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