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SC 435

Known as: SC-435, SC435 
National Institutes of Health

Papers overview

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Review
2020
Review
2020
[The inhibitors of the apical sodium-dependent bile acid transporter (ASBT) as promising drugs].
Inhibition of the apical sodium-dependent bile acid transporter (ASBT, also known as IBAT - ileal bile acid transporter, SLC10A2… 
2005
2005
Effect of SC-435 on the gastrointestinal migrating myoelectric complex in guinea pigs.
OBJECTIVE To determine whether SC-435, a new ileal apical sodium-codependent bile acid transporter (IBAT) inhibitor, can alter… 
Highly Cited
2004
Highly Cited
2004
Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7 alpha-hydroxylase.
2004
2004
SC-435, an ileal apical sodium co-dependent bile acid transporter (ASBT) inhibitor: Hypocholesterolemic mechanisms of action in the guinea pig
2003
2003
Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB Published, JLR Papers in Press, February 1, 2003. DOI 10.1194…
Discovery of the ileal apical sodium-dependent bile acid transporter (ASBT) permitted development of specific inhibitors of bile… 
2002
2002
octane Methanesulfonate ( SC-435 ) , an Ileal Apical Sodium-Codependent Bile Acid Transporter Inhibitor Alters Hepatic Cholesterol Metabolism and Lowers Plasma Low-Density Lipoprotein-Cholesterol…
  • 2002
  • Corpus ID: 27323572
Male Hartley guinea pigs (10/group) were assigned either to a control diet (no drug treatment) or to diets containing 0.4, 2.2… 
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