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SC 41661A

Known as: 3-(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)thiol-N- methyl-N-((2-pyridinyl)propanamide) hydrochloride, SC-41661A, SC41661A 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

AmidesPyridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Increased cytosol Ca(2+) and type 1 programmed cell death in Bcl-2-positive U937 but not in Bcl-2-negative PC-3 and Panc-1 cells induced by the 5-lipoxygenase inhibitor MK 886.
MK 886, an arachidonic acid-related analog which inhibits the enzyme, 5-lipoxygenase by an indirect mechanism involving the 5… 
2001
2001
The mode of cell death in H-358 lung cancer cells cultured with inhibitors of 5-lipoxygenase or the free radical spin trap, NTBN.
1999
1999
Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid.
The five-lipoxygenase inhibitors ETYA, SC41661A and MK 886 reduced the proliferation and viability of Panc-1 human pancreatic… 
Highly Cited
1998
Highly Cited
1998
5‐lipoxygenase inhibitors reduce PC‐3 cell proliferation and initiate nonnecrotic cell death
Products of the arachidonic acid‐metabolizing enzyme, 5‐lipoxygenase, stimulate the growth of several cell types. Selective… 
1998
1998
Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid.
The 5-lipoxygenase inhibitors ETYA, SC41661A and MK886 reduced the proliferation and viability of Panc-1 human pancreatic cancer… 
1994
1994
Contrasting effects of two arachidonate 5-lipoxygenase inhibitors on formyl-methionyl-leucyl-phenylalanine (fMLP) and complement fragment 5a induced human neutrophil superoxide generation.
1993
1993
Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase.
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