SC-2001
National Institutes of Health
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Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA
Regulatory factor X (RFX) 1 is a transcription…
Interfering oncogenic STAT3 signaling is a promising anti-cancer strategy. We examined the efficacy and drug mechanism of an…
Obatoclax is a small molecule which targets the Bcl-2 family, and is to treat leukemia, lymphoma and lung carcinoma. Previously…
Interfering oncogenic STAT3 signaling is a promising anti-cancer strategy. We examined the efficacy and drug mechanism of an…
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA
Background: Interfering the oncogenic STAT3 signaling is…
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA
Obatoclax is under clinical trial currently. Previously…
Background: STAT3 has been shown to play an important role in breast carcinogenesis and is often overexpressed in primary breast…
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL
The activation of signal transducers and activators of…
Background: Our previous work showed that bortezomib, a reverse-inhibitor of the 26S proteasome, exerts differential cytotoxic…