SB 649868

Known as: SB-649868, SB649868 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2017
02420102017

Papers overview

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2014
2014
The orexin-hypocretin system is important for translating peripheral metabolic signals and central neuronal inputs to a diverse… (More)
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2014
2014
In accordance with the prominent role of orexins in the maintenance of wakefulness via activation of orexin-1 (OX1R) and orexin-2… (More)
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2013
2013
Dual orexin receptor (OXR) antagonists (DORAs) such as almorexant, 1 (SB-649868), or suvorexant have shown promise for the… (More)
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2012
2012
STUDY OBJECTIVES To assess the acute effects of SB-649868 in male subjects with Primary Insomnia with regard to (1) objective and… (More)
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2012
2012
The orexin system plays a major role in the integration of metabolic and circadian influences that drive wakefulness. This paper… (More)
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2012
2012
Orexins have a role in sleep regulation, and orexin receptor antagonists are under development for the treatment of insomnia. We… (More)
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2012
2012
Orexins (OX) and their receptors (OXR) modulate feeding, arousal, stress, and drug abuse. Neural systems that motivate and… (More)
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2012
2012
In this work the pharmacology and the receptor kinetics of the following orexin receptor antagonists SB-649868, ACT-078573, JNJ… (More)
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2011
2011
N-[[(2S)-1-[[5-(4-fluorophenyl)-2-methyl-4-thiazolyl]carbonyl]-2-piperidinyl]methyl]-4-benzofurancarboxamide (SB-649868) is a… (More)
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2010
2010
N-[[(2S)-1-[[5-(4-fluorophenyl)-2-methyl-4-thiazolyl]carbonyl]-2piperidinyl]methyl]-4-benzofurancarboxamide (SB-649868) is a… (More)
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