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SAV1 gene

Known as: WW45, WWP4, WW domain-containing adaptor 45 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Hippo Pathway Deficiency Reverses Systolic Heart Failure Post-Infarction
Mammalian organs vary widely in regenerative capacity. Poorly regenerative organs, such as the heart are particularly vulnerable… 
Highly Cited
2012
Highly Cited
2012
The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.
Highly Cited
2011
Highly Cited
2011
A comparative study of marine salmonid alphavirus subtypes 1-6 using an experimental cohabitation challenge model.
A comparative challenge study of six marine isolates representing subtypes 1-6 of salmonid alphavirus (salmon pancreas disease… 
Highly Cited
2009
Highly Cited
2009
Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines.
The Salvador/Warts/Hippo (SWH) pathway is an important modulator of organ size, and deregulation of pathway activity can lead to… 
Highly Cited
2008
Highly Cited
2008
A crucial role of WW45 in developing epithelial tissues in the mouse
The role and molecular mechanisms of a new Hippo signalling pathway are not fully understood in mammals. Here, we generated mice… 
Highly Cited
2007
Highly Cited
2007
RASSF1A Is Part of a Complex Similar to the Drosophila Hippo/Salvador/Lats Tumor-Suppressor Network
Highly Cited
2007
Highly Cited
2007
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
In eukaryotic cells, apoptosis and cell cycle arrest by the Ras → RASSF → MST pathway are controlled by the interaction of SARAH… 
Highly Cited
2006
Highly Cited
2006
The Drosophila RASSF Homolog Antagonizes the Hippo Pathway
Review
2003
Review
2003
A novel inter action motif, SARAH, connects three classes of tumor suppressor
Highly Cited
2001
Highly Cited
2001
CdSe−ZnS Quantum Dots as Resonance Energy Transfer Donors in a Model Protein−Protein Binding Assay
Specific binding of biotinilated bovine serum albumin (bBSA) and tetramethylrhodamine-labeled streptavidin (SAv−TMR) was observed… 
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