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SAMHD1, IVS14AS, G-C, -1

National Institutes of Health

Related topics

Related topics

1 relation
AICARDI-GOUTIERES SYNDROME 5 (disorder)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A SAMHD1 mutation associated with Aicardi–Goutières syndrome uncouples the ability of SAMHD1 to restrict HIV‐1 from its ability to downmodulate type I interferon in humans
Mutations in the human SAMHD1 gene are known to correlate with the development of the Aicardi–Goutières syndrome (AGS), which is… Expand
2016
2016
Substrate Specificity of SAMHD1 Triphosphohydrolase Activity Is Controlled by Deoxyribonucleoside Triphosphates and Phosphorylation at Thr592.
The sterile alpha motif (SAM) and histidine-aspartate (HD) domain containing protein 1 (SAMHD1) constitute a triphosphohydrolase… Expand
2015
2015
Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs☆
Understanding how to achieve efficient transduction of hematopoietic stem and progenitor cells (HSPCs), while preserving their… Expand
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Highly Cited
2013
Highly Cited
2013
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
SAMHD1 is a dGTP-activated deoxynucleoside triphosphate triphosphohydrolase (dNTPase) whose dNTPase activity has been linked to… Expand
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