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SALL2 gene

Known as: spalt-like transcription factor 2, SAL-LIKE 2, SALL2 
This gene is involved in the modulation of gene expression.
National Institutes of Health

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Homo sapiensSALL2 protein, humanTranscriptional Regulationdna binding

Papers overview

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2019
2019
Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer
Resistance to tamoxifen is a clinically major challenge in breast cancer treatment. Although downregulation of estrogen receptor… 
2018
2018
Computational identification of specific genes for glioblastoma stem-like cells identity
Glioblastoma, the most malignant brain cancer, contains self-renewing, stem-like cells that sustain tumor growth and therapeutic… 
Highly Cited
2017
Highly Cited
2017
Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia
Significance To get more insights into the disease mechanism of T-cell acute lymphoblastic leukemia (T-ALL), particularly in an… 
2009
2009
Sall2 is a novel p75NTR‐interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth
By screening a fetal brain two‐hybrid library with the death domain of the p75 neurotrophin receptor (NTR), we identified the… 
Highly Cited
2005
Highly Cited
2005
Gene expression profiling of human sarcomas: insights into sarcoma biology.
Sarcomas are a biologically complex group of tumors of mesenchymal origin. By using gene expression microarray analysis, we aimed… 
Highly Cited
2004
Highly Cited
2004
SALL4 deletions are a common cause of Okihiro and acro-renal-ocular syndromes and confirm haploinsufficiency as the pathogenic mechanism
23 and mutations at SALL4 have been shown to be causative in patients with Okihiro/Duane-radial ray syn- drome (OMIM No 607323… 
2003
2003
Zinc Finger Protein Sall2 Is Not Essential for Embryonic and Kidney Development
ABSTRACT SALL/Sall is a mammalian homolog of the Drosophila region-specific homeotic gene spalt (sal), and heterozygous mutations… 
Review
2002
Review
2002
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition.
2001
2001
Cloning and Characterization of Two Promoters for the Human HSAL2 Gene and Their Transcriptional Repression by the Wilms Tumor Suppressor Gene Product*
HSAL2 is a member of a gene family that encodes a group of putative developmental transcription factors. The HSAL gene complex… 
Highly Cited
1999
Highly Cited
1999
SALL3, a new member of the human spalt-like gene family, maps to 18q23.
spalt (sal) of Drosophila melanogaster is an important developmental regulator gene and encodes a zinc finger protein of unusual… 
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