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SAA1 gene

Known as: AMYLOID A, SERUM, TP53I4, SAA 
National Institutes of Health

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3 relations
Amyloid A MeasurementSAA@ gene clusterSerum amyloid A protein

Papers overview

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Highly Cited
2018
Highly Cited
2018
Serum amyloid A promotes LPS clearance and suppresses LPS‐induced inflammation and tissue injury
Lipopolysaccharide (LPS) is a major microbial mediator for tissue injury and sepsis resulting from Gram‐negative bacterial… 
Highly Cited
2014
Highly Cited
2014
Inflammation-Induced Acute Phase Response in Skeletal Muscle and Critical Illness Myopathy
Objectives Systemic inflammation is a major risk factor for critical-illness myopathy (CIM) but its pathogenic role in muscle is… 
Highly Cited
2009
Highly Cited
2009
IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.
Animal studies suggest that increased levels of circulating angiotensin II (AngII) could contribute to the loss of lean body mass… 
Highly Cited
2006
Highly Cited
2006
Significance of SAA1.3 allele genotype in Japanese patients with amyloidosis secondary to rheumatoid arthritis.
OBJECTIVE To clarify the clinical significance of the SAA1.3 allele in the development and outcome of AA amyloidosis in Japanese… 
Highly Cited
2004
Highly Cited
2004
Regulation of the Human Acute Phase Serum Amyloid A Genes by Tumour Necrosis Factor‐α, Interleukin‐6 and Glucocorticoids in Hepatic and Epithelial Cell Lines
The major acute‐phase protein serum amyloid A, A‐SAA, is upregulated by a variety of inflammatory stimuli, including cytokines… 
Review
2003
Review
2003
The contribution of genotypes at the MEFV and SAA1 loci to amyloidosis and disease severity in patients with familial Mediterranean fever.
OBJECTIVE The clinical profile in familial Mediterranean fever (FMF), including its major manifestation, amyloidosis, is… 
Highly Cited
1998
Highly Cited
1998
SAA1 alleles as risk factors in reactive systemic AA amyloidosis.
SAA1 is the predominant isoform of acute phase human SAA deposited as AA amyloid fibrils in reactive systemic amyloidosis. It has… 
Highly Cited
1995
Highly Cited
1995
Characterization of amyloid A protein in human secondary amyloidosis: the predominant deposition of serum amyloid A1.
Highly Cited
1988
Highly Cited
1988
Circular-dichroism studies on two murine serum amyloid A proteins.
C.d. studies have shown that mouse SAA2 (serum amyloid A2) protein has about one-half of the alpha-helix content of the SAA1… 
Highly Cited
1985
Highly Cited
1985
Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.
cDNA clones encoding two major mouse serum amyloid A proteins, SAA1 and SAA2, were isolated from a liver cDNA library of the… 
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