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S 14161

Known as: S-14161, S14161 
 
National Institutes of Health

Papers overview

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2019
2019
The small chemical compound 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene (S14161) was recently identified as an inhibitor of… Expand
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2017
2017
S14161 is a pan-Class I PI3K inhibitor that induces blood cancer cell death, but its mechanism is largely unknown. In the present… Expand
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2017
2017
BACKGROUND Coumarins possess a broad spectrum of biological activities and are important pharmacophores in drug developments… Expand
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2015
2015
Side population (SP) cells are an enriched source of cancer-initiating cells with stemness characteristics, generated by… Expand
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2014
2014
BackgroundWe previously reported a PI3K inhibitor S14161 which displays a promising preclinical activity against multiple myeloma… Expand
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2014
2014
The phosphatidylinositol 3–kinase (PI3K) signaling pathway is critical in modulating platelet functions. In the present study, we… Expand
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2014
2014
Recent studies demonstrated that targeting the phosphatidylinositide 3-kinase (PI3K)/AKT signaling pathway is a major strategy… Expand
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2013
2013
The small chemical compound 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene (S14161) was recently identified as an inhibitor of… Expand
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2013
2013
BackgroundLup-20(29)-en-3H-ol (Lupeol), a dietary triterpene, has been shown to possess multiple pharmacological activities… Expand
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2011
2011
D-cyclins are universally dysregulated in multiple myeloma and frequently overexpressed in leukemia. To better understand the… Expand
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