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S-(1,2-dichlorovinyl)cysteine

Known as: 1,2-DCVC, 1,2-dichlorovinyl-L-cysteine, S-(2,2-dichlorovinyl)-L-cysteine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Cysteine
analogs & derivatives

Papers overview

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2009
2009
Alterations of the renal function in the isolated perfused rat kidney system after in vivo and in vitro application of S-(1,2-dichlorovinyl)-L-cysteine and S-(2,2-dichlorovinyl)-L-cysteine
The nephrotoxic effects of the two isomers S-(1,2-dichlorovinyl)-l-cysteine (1,2-DCVC) and S-(2,2-dichlorovinyl)-l-cysteine (2,2… Expand
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1997
1997
Biotransformation, excretion and nephrotoxicity of haloalkene-derived cysteine S-conjugates
Abstract The formation of cysteine S-conjugates is thought to play an important role in the nephrotoxicity of haloalkenes such as… Expand
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1993
1993
Purification of glutamine transaminase K/cysteine conjugate beta-lyase from rat renal cytosol based on hydrophobic interaction HPLC and gel permeation FPLC.
Cysteine conjugate beta-lyase (beta-lyase, EC 4.4.1.13) was purified to homogeneity from rat renal cytosol using a new and highly… Expand
1993
1993
Examination of the structure-toxicity relationships of L-cysteine-S-conjugates of halogenated alkenes and their corresponding mercapturic acids in rat renal tissue slices.
Rat kidney slices were produced using a modified version of a mechanical tissue slicer. The slices were incubated with various… Expand
1991
1991
Acute effects of the D-isomer of S-(1,2-dichlorovinyl)cysteine on renal function and ultrastructure in the pentobarbital-anesthetized dog: site-specific toxicity involving the S1 and S2 cells of the…
Intravenous doses of 92.6 and 185.2 mumol S-(1,2-dichlorovinyl)-D-cysteine (D-DCVC)/kg were acutely nephrotoxic in pentobarbital… Expand
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