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Rifalazil

Known as: 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin, 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin, benzoxazinorifamycin 
 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The first antibiotic of the ansamycin family, rifampicin (RIF), was isolated in 1959 and was introduced into therapy in 1962; it… Expand
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Highly Cited
2007
Highly Cited
2007
The incidence and severity of Clostridium difficile-associated disease (CDAD) is increasing, and standard treatment is not always… Expand
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2007
2007
OBJECTIVES To determine the safety and effectiveness of single-dose rifalazil, a new rifamycin, for the treatment of… Expand
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2005
2005
Although rifamycins have excellent activity against Chlamydophila pneumoniae and Chlamydia trachomatis in vitro, concerns about… Expand
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2004
2004
Although vancomycin and metronidazole effectively treat Clostridium difficile-associated diarrhea and colitis (CDAD), their use… Expand
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Review
2003
Review
2003
Rifalazil represents a new generation of ansamycins that contain a unique four-ring structure. Originally rifalazil was developed… Expand
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2001
2001
Rifalazil, also known as KRM-1648 or benzoxazinorifamycin, is a new semisynthetic rifamycin with a long half-life of… Expand
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2000
2000
Rifalazil (formerly known as KRM-1648) in combination with isoniazid has been found to be more active than rifampin/isoniazid… Expand
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1998
1998
1. The effect of a new rifamycin derivative, rifalazil (KRM-1648), on liver microsomal enzyme induction was studied in rat and… Expand
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