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Rifalazil

Known as: 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin, 3'-hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin, benzoxazinorifamycin 
 
National Institutes of Health

Papers overview

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2013
2013
Rifampin, a semisynthetic rifamycin, is the cornerstone of current tuberculosis treatment. Among many semisynthetic rifamycins… Expand
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2008
2008
Osteomyelitis represents a challenge to modern medicine. This inflammatory process is accompanied by bone necrosis, and results… Expand
Highly Cited
2007
Highly Cited
2007
ABSTRACT The incidence and severity of Clostridium difficile-associated disease (CDAD) is increasing, and standard treatment is… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Although vancomycin and metronidazole effectively treat Clostridium difficile-associated diarrhea and colitis (CDAD… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT Rifalazil, also known as KRM-1648 or benzoxazinorifamycin, is a new semisynthetic rifamycin with a long half-life of… Expand
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Highly Cited
1997
Highly Cited
1997
The protease inhibitors, ritonavir, indinavir and saquinavir, the most potent anti-HIV drugs developed to date, interact with… Expand
1995
1995
We investigated the activity of benzoxazinorifamycin (KRM-1648) against several drug-susceptible and multidrug-resistant strains… Expand
Highly Cited
1995
Highly Cited
1995
The in vitro and in vivo activities of a new benzoxazinorifamycin, KRM-1648 (KRM), against Mycobacterium tuberculosis were… Expand
1993
1993
As a part of our studies on the syntheses of benzoxazinorifamycin derivatives, 3'-hydroxy-5'-aminobenzoxazinorifamycin… Expand
Highly Cited
1992
Highly Cited
1992
Newly synthesized benzoxazinorifamycin, KRM-1648, was studied for its in vivo anti-Mycobacterium avium complex (MAC) activities… Expand
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