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RibCys

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.
2004
2004
L-Cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity
Summary2(R,S)-d-ribo-(1′,2′,3′,4′-Tetrahydroxybutyl)-thiazolidine-4(R)-carboxylic acid (RibCys) is a prodrug ofL-cysteine that… 
2003
2003
The “Pro-drug” RibCys Decreases the Mutagenicity of High-LET Radiation in Cultured Mammalian Cells
Abstract Lenarczyk, M., Ueno, A., Vannais, D. B., Kraemer, S., Kronenberg, A., Roberts, J. C., Tatsumi, K., Hei, T. K. and… 
2002
2002
Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.
It has been reported that X-ray induced HPRT- mutation in cultured human cells is prevented by ascorbate added after irradiation… 
2001
2001
Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.
Representatives of two classes of thiazolidine prodrug forms of the well-known radioprotective agents L-cysteine, cysteamine, and… 
2001
2001
Vitamin C (AsA) and Ribcys reduce the mutagenicity of LET 100 carbon even when added after irradiation
1995
1995
Thiazolidine prodrugs of cysteamine and cysteine as radioprotective agents.
The need for protection against the toxic effects of ionizing radiation comes from many different directions: occupational… 
1994
1994
Chemoprotection against cyclophosphamide-induced urotoxicity: ribose-cysteine.
2(R,S)-D-ribo-(1',2',3',4'-tetrahydroxybutyl) thiazolidine-4(R)-carboxylic acid (RibCys) is a prodrug of L-cysteine, which can… 
1992
1992
Failure of glutathione and cysteine prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo.
1991
1991
Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys.
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