Reolysin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
0520022017

Papers overview

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2016
2016
Pelareorep causes oncolysis in tumor cells with activated Ras. We hypothesized that pelareorep would have efficacy and… (More)
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2015
2015
Activating mutations in RAS are present in the majority of pancreatic cancer cases and represent an ideal therapeutic target… (More)
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2015
2015
BACKGROUND Reovirus is a naturally occurring human virus that is cytopathic to malignant cells possessing an activated Ras… (More)
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2014
2014
PURPOSE Reolysin, a proprietary isolate of reovirus type III dearing, enters and preferentially induces apoptosis of malignant… (More)
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2013
2013
Activating mutation of KRas is a genetic alteration that occurs in the majority of pancreatic tumors and is therefore an ideal… (More)
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2011
2011
BACKGROUND Despite advancement in therapies, overall survival rates for relapsed pediatric sarcomas are dismal. Newer therapies… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE REOLYSIN (Oncolytics Biotech) consists of a wild-type oncolytic reovirus, which has selective cytotoxicity for tumor… (More)
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2009
2009
Background Reolysin® is reovirus serotype 3-Dearing strain, a double-stranded replication-competent RNA non-enveloped icosahedral… (More)
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2009
2009
10524 Background: Reolysin is a Dearing strain, naturally occurring, ubiquitous human reovirus. The PKR (double stranded RNA… (More)
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2005
2005
BACKGROUND The purpose of this study was to evaluate the individualized and standardized quality of life (QL) and psychological… (More)
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