Refractory anaemia with excess blasts

Known as: Leukemias, Smoldering, Refractory Anemia with Excess Blasts, Smoldering Leukemia 
A myelodysplastic syndrome characterized by the presence of 5-19% myeloblasts in the bone marrow or 2-19% blasts in the peripheral blood. It includes… (More)
National Institutes of Health

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AgranulocytosisAnemiaBone MarrowBone marrow stem cell
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RAEB-1RAEB-2

Papers overview

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Highly Cited
2009
Highly Cited
2009
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.
Myelodysplastic syndromes (MDSs) are clonal hematologic disorders that frequently represent an intermediate disease stage before… (More)
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Highly Cited
2009
Highly Cited
2009
A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS.
This study investigated the immunogenicity of Wilms tumor gene product 1 (WT1)-peptide vaccination in WT1-expressing acute… (More)
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Highly Cited
2004
Highly Cited
2004
High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia.
A high incidence of somatically acquired point mutations in the AML1/RUNX1 gene has been reported in poorly differentiated acute… (More)
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Review
2002
Review
2002
Results of treatment of children with refractory anaemia with excess blasts (RAEB) and RAEB in transformation (RAEBt) in Great Britain 1990-99.
Between 1990 and 1999, 36 children with refractory anaemia with excess blasts (RAEB) and RAEB in transformation (RAEBt), not… (More)
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Highly Cited
2001
Highly Cited
2001
Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes.
Vascular endothelial growth factor (VEGF) is a potent angiogenic peptide with biologic effects that include regulation of… (More)
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Highly Cited
2000
Highly Cited
2000
The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS.
Bone marrow CD34(+) cell apoptosis (annexin V), proliferation (Ki-67), and Bcl-2-related protein expression was evaluated by flow… (More)
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1993
1993
Immunotyping of blasts in refractory anaemia with excess of blasts.
A study of immunological markers was performed in 16 patients with newly diagnosed refractory anaemia with excess of blasts (RAEB… (More)
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1987
1987
Successful oral chemotherapy with idarubicin in refractory anaemia with excess blasts.
6 patients with refractory anaemia with excess blasts (RAEB) were treated with a new oral anthracycline, idarubicin. 3 patients… (More)
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Highly Cited
1987
Highly Cited
1987
Effects of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes.
The myelodysplastic syndromes are characterized by ineffective hematopoiesis and refractory cytopenias. In an attempt to improve… (More)
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Highly Cited
1982
Highly Cited
1982
Proposals for the classification of the myelodysplastic syndromes.
New diagnostic criteria for the diagnosis of the various myelodysplastic syndromes (MDS) are proposed, and a detailed description… (More)
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