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Recombinant Lymphotoxin Beta

Known as: Lymphotoxin Beta, TNFC, Tumor Necrosis Factor C 
Lymphotoxin is a cytokine that orchestrates lymphoid neogenesis and is present on the surface of activated T-, B-, and LAK cells as a heterotrimer of… Expand
National Institutes of Health

Related topics

Related topics

4 relations
LTB geneLTB protein, humanLTB wt Allelelymphotoxin beta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Therapeutic efficacy of a multi-epitope vaccine against Helicobacter pylori infection in BALB/c mice model.
Epitope vaccine is a promising option for therapeutic vaccination against Helicobacter pylori (H. pylori) infection. In this… Expand
2006
2006
Expression of lymphotoxin beta governs immunity at two distinct levels
Interaction of lymphotoxin α1β2 (LTα1β2) with its receptor is key for the generation and maintenance of secondary lymphoid organ… Expand
Highly Cited
2004
Highly Cited
2004
Lymphotoxin beta receptor signaling induces the chemokine CCL20 in intestinal epithelium.
BACKGROUND & AIMS The follicle-associated epithelium (FAE) that overlies Peyer's patches (PPs) exhibits distinct features… Expand
2004
2004
MAdCAM-1 Expressing Sacral Lymph Node in the Lymphotoxin β-Deficient Mouse Provides a Site for Immune Generation Following Vaginal Herpes Simplex Virus-2 Infection1
The members of the lymphotoxin (LT) family of molecules play a critical role in lymphoid organogenesis. Whereas LTα-deficient… Expand
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2003
2003
Upregulation of lymphotoxin beta expression in liver progenitor (oval) cells in chronic hepatitis C.
BACKGROUND Bipotent liver progenitor (oval) cells with the ability to differentiate into hepatocytes and biliary epithelium have… Expand
Highly Cited
1999
Highly Cited
1999
TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes.
Inactivation of genes encoding members of TNF and TNF receptor families reveal their divergent roles in the formation and… Expand
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Highly Cited
1997
Highly Cited
1997
Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice.
The tumor necrosis factor (TNF) family cytokines lymphotoxin (LT) alpha and LTbeta form heterotrimers that are expressed on the… Expand
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Highly Cited
1997
Highly Cited
1997
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice.
Lymphotoxin alpha (LT alpha)-deficient mice revealed critical roles for LT alpha in lymphoid organogenesis, but it is not clear… Expand
1996
1996
Preparation and Characterization of Soluble Recombinant Heterotrimeric Complexes of Human Lymphotoxins and (*)
The lymphotoxin (LT) protein complex is a heteromer of α (LT-α, also called tumor necrosis factor (TNF)-β) and β (LT-β) chains… Expand
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Highly Cited
1991
Highly Cited
1991
Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes.
We have identified three polymorphic microsatellites (which we call TNFa, TNFb, and TNFc) within a 12-kilobase region of the… Expand
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