FAQ

Recombinant Lymphotoxin Beta

Known as: Lymphotoxin Beta, TNFC, Tumor Necrosis Factor C 
Lymphotoxin is a cytokine that orchestrates lymphoid neogenesis and is present on the surface of activated T-, B-, and LAK cells as a heterotrimer of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2011
02419942011

Related topics

Related topics

4 relations
LTB geneLTB protein, humanLTB wt Allelelymphotoxin beta

Related mentions per year

Related mentions per year

1959-2018
1960198020002020
Recombinant Lymphotoxin Beta
LTB protein, human
LTB gene
lymphotoxin beta
LTB wt Allele

Papers overview

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Highly Cited
2005
Highly Cited
2005
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
TGF-beta-activated kinase 1 (TAK1), a member of the MAPKKK family, is thought to be a key modulator of the inducible… (More)
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Highly Cited
2003
Highly Cited
2003
Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism.
The 'classical' NF-kappaB activation pathway proceeds via IkappaB kinase (IKK)-beta/gamma-mediated phosphorylation, induced… (More)
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2002
2002
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion.
Transmissible spongiform encephalopathy or prion diseases are fatal neurodegenerative disorders of humans and animals often… (More)
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Highly Cited
2001
Highly Cited
2001
Lymphoid neogenesis in rheumatoid synovitis.
In rheumatoid arthritis (RA), tissue-infiltrating lymphocytes can be arranged in sophisticated organizations that resemble… (More)
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1998
1998
Effects of tumor necrosis factor and lymphotoxin on peripheral lymphoid tissue development.
Previously, we have reported that neutralization of surface lymphotoxin (LT-alphabeta) in mice which expressed an LT-beta… (More)
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Highly Cited
1997
Highly Cited
1997
A Critical Role for Lymphotoxin in Experimental Allergic Encephalomyelitis
The lymphotoxin (LT)/tumor necrosis factor (TNF) family has been implicated in the neurologic inflammatory diseases multiple… (More)
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1995
1995
Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors.
Lymphotoxin (LT) is a cytokine related to TNF, found in human systems in both secreted and membrane bound forms. The well… (More)
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Highly Cited
1994
Highly Cited
1994
A lymphotoxin-beta-specific receptor.
Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha) are members of a family of secreted and cell surface cytokines that… (More)
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1994
1994
Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells.
Transcription of the human tumor necrosis factor alpha (TNF-alpha) gene is one of the earliest events that occurs after… (More)
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1994
1994
CD40 ligation induces lymphotoxin alpha gene expression in human B cells.
CD40 plays an important role in T cell mediated B cell proliferation and isotype switching. The cytokines tumor necrosis factor… (More)
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