Receptors, Colony-Stimulating Factor

Known as: Colony-Stimulating Factor Receptors, CSF Receptor, Colony Stimulating Factor Receptor Family 
A group of proteins found on the surface of hematopoietic cells that bind to colony stimulating factors and other ligands to regulate cellular… (More)
National Institutes of Health

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22 relations
CSF1R geneCell Differentiation processCell ProliferationColony-Stimulating Factors
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Papers overview

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Highly Cited
2006
Highly Cited
2006
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
BACKGROUND The JAK2V617F allele has recently been identified in patients with polycythemia vera (PV), essential thrombocytosis… (More)
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Highly Cited
1998
Highly Cited
1998
Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor.
The escape of malignant cells from the immune response against the tumor may result from a defective differentiation or function… (More)
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Highly Cited
1996
Highly Cited
1996
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter.
Transcription factors play a key role in the development and differentiation of specific lineages from multipotential progenitors… (More)
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Highly Cited
1994
Highly Cited
1994
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.
The macrophage colony-stimulating factor (M-CSF) receptor is expressed in a tissue-specific fashion from two distinct promoters… (More)
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Highly Cited
1994
Highly Cited
1994
Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia.
Severe congenital neutropenia (Kostmann syndrome) is characterized by profound absolute neutropenia and a maturation arrest of… (More)
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Highly Cited
1993
Highly Cited
1993
Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor
Granulocyte colony-stimulating factor (G-CSF) is a cytokine that regulates the proliferation and differentiation of neutrophils… (More)
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Highly Cited
1992
Highly Cited
1992
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.
We have cloned the human homolog of the v-mpl oncogene transduced in the myeloproliferative leukemia retrovirus, which presents… (More)
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Highly Cited
1991
Highly Cited
1991
Functional domains of the granulocyte colony-stimulating factor receptor.
The granulocyte colony-stimulating factor (G-CSF) receptor has a composite structure consisting of an immunoglobulin(Ig)-like… (More)
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Highly Cited
1990
Highly Cited
1990
Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.
Three cDNAs for the human granulocyte colony-stimulating factor (G-CSF) receptor were isolated from the cDNA libraries of human… (More)
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Highly Cited
1990
Highly Cited
1990
Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.
Using the mouse interleukin 3 (IL-3) receptor cDNA as a probe, we obtained a homologous cDNA (KH97) from a cDNA library of a… (More)
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