Receptor, EphA2

Known as: EphA2 Receptor Tyrosine Kinase, EphA2 Tyrosine Kinase, Receptor, EphA2 [Chemical/Ingredient] 
An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
02420032018

Papers overview

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2017
2017
Metadynamics (META-D) is emerging as a powerful method for the computation of the multidimensional free-energy surface (FES… (More)
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2016
2016
Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal ectodomain binds ligands and enables receptor… (More)
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2016
2016
The free-energy surface (FES) of protein-ligand binding contains information useful for drug design. Here we show how to exploit… (More)
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2015
2015
The EphA2 receptor tyrosine kinase promotes cell migration and cancer malignancy through a ligand- and kinase-independent… (More)
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2015
2015
BACKGROUND Eph receptors and ephrin ligands have several functions including angiogenesis, cell migration, axon guidance, fluid… (More)
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2014
2014
INTRODUCTION EphA2, one member of the Eph receptor family, is widely expressed in multiple aggressive cancers. SWL, a small… (More)
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2014
2014
BACKGROUND We have previously shown that EphrinA1/EphA expression profile changes in response to myocardial infarction (MI… (More)
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2013
2013
Ephrin (Eph) signaling within the central nervous system is known to modulate axon guidance, synaptic plasticity, and to promote… (More)
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2013
2013
Designing potent and selective peptides and small molecules that target Eph receptor tyrosine kinases remains a challenge and new… (More)
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2012
2012
During tumor progression, EphA2 receptor can gain ligand-independent pro-oncogenic functions due to Akt activation and reduced… (More)
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