Receptor, Cannabinoid, CB2

Known as: Receptor, CB2, Receptor, Cannabinoid, CB2 [Chemical/Ingredient], Cannabinoid Receptor CB2 
A subclass of cannabinoid receptor found primarily on immune cells where it may play a role modulating release of CYTOKINES.
National Institutes of Health

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CNR2 geneIn BloodPCDHA6 geneagonists
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Brain Cannabinoid CB2 Receptors Modulate Cocaine’s Actions in Mice
The presence and function of cannabinoid CB2 receptors in the brain have been the subjects of much debate. We found that systemic… (More)
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Highly Cited
2007
Highly Cited
2007
Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.
BACKGROUND AND PURPOSE A nonpsychoactive constituent of the cannabis plant, cannabidiol has been demonstrated to have low… (More)
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Highly Cited
2006
Highly Cited
2006
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
Brain expression of CB2 cannabinoid receptors has been much less well established and characterized in comparison to the… (More)
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Review
2006
Review
2006
Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain.
Two well-characterized cannabinoid receptors (CBrs), CB1 and CB2, mediate the effects of cannabinoids and marijuana use, with… (More)
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Highly Cited
2006
Highly Cited
2006
Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain.
For over a decade, until recently, it was thought that marijuana acts by activating brain-type cannabinoid receptors called CB1… (More)
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Highly Cited
2005
Highly Cited
2005
Antifibrogenic role of the cannabinoid receptor CB2 in the liver.
BACKGROUND & AIMS Hepatic myofibroblasts are central for the development of liver fibrosis associated with chronic liver diseases… (More)
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Highly Cited
2005
Highly Cited
2005
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.
The cannabinoid system is known to be important in neuronal regulation, but is also capable of modulating immune function… (More)
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Highly Cited
2003
Highly Cited
2003
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS.
We designed AM1241, a selective CB2 cannabinoid receptor agonist, and used it to test the hypothesis that CB2 receptor activation… (More)
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Highly Cited
2001
Highly Cited
2001
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
The development of new therapeutic strategies is essential for the management of gliomas, one of the most malignant forms of… (More)
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Highly Cited
1995
Highly Cited
1995
Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations.
Two proteins with seven transmembrane-spanning domains typical of guanosine-nucleotide-binding-protein-coupled receptors have… (More)
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