Ras Inhibitor

An agent designed to inhibit the signal transduction process by interfering with the action of the ras protein.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
01219972018

Papers overview

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2017
2017
Background Inhibition of the renin-angiotensin system (RAS) was associated with longer survival in patients with different solid… (More)
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2016
2016
Cyclic peptides have great potential as therapeutic agents and research tools. However, their applications against intracellular… (More)
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2016
2016
Histone deacetylase inhibitors (HDIs) represent a new class of anticancer drugs. Suberoylanilide hydroxamic acid (SAHA), the… (More)
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2014
2014
I have utilized genetically engineered mouse models of pancreatic cancer to identify a potential new therapeutic target, and to… (More)
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2013
2013
BACKGROUND AND AIM The chemopreventive effect of RAS inhibitors on colorectal cancer is unknown. Because aberrant crypt foci (ACF… (More)
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2007
2007
Deregulation of Ras pathways results in complex abnormalities of multiple signaling cascades that contribute to human… (More)
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2005
2005
OBJECTIVE To examine the role of the phospho-inositol-3'-kinase (PI3-K)-akt signaling axis during smooth muscle cell (SMC… (More)
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2003
2003
This study was undertaken to determine whether the response of smooth muscle cells to mitogens can be inhibited by inactivating… (More)
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1998
1998
Tyrosinase-related protein 2 (TRP-2)/DOPAchrome tautomerase is an enzyme involved in melanin biosynthesis and plays an important… (More)
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