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Rad51B-Rad51C-Rad51D-XRCC2 complex
Known as:
BCDX2 complex
, BCDX2 complex location
, Rad51B-Rad51C-Rad51D-XRCC2 complex location
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof. [GOC:mah, PMID:16093548…
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National Institutes of Health
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Highly Cited
2012
Highly Cited
2012
Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway
Jarin Chun
,
Erika S. Buechelmaier
,
S. Powell
Molecular and Cellular Biology
2012
Corpus ID: 10342012
ABSTRACT The Rad51 paralogs are required for homologous recombination (HR) and the maintenance of genomic stability. The…
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2010
2010
Ring-shaped Rad51 Paralog Protein Complexes Bind Holliday Junctions and Replication Forks as Visualized by Electron Microscopy*
Sarah A. Compton
,
Sezgin Özgür
,
J. Griffith
Journal of Biological Chemistry
2010
Corpus ID: 20558501
In mammals, there are five Rad51 paralogs that form two distinct complexes in vivo. One complex is composed of Rad51B-Rad51C…
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Highly Cited
2007
Highly Cited
2007
Role of RAD51C and XRCC3 in Genetic Recombination and DNA Repair*
Yilun Liu
,
M. Tarsounas
,
Paul O'Regan
,
S. West
Journal of Biological Chemistry
2007
Corpus ID: 25244104
In germ line cells, recombination is required for gene reassortment and proper chromosome segregation at meiosis, whereas in…
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Highly Cited
2004
Highly Cited
2004
Human Rad51C Deficiency Destabilizes XRCC3, Impairs Recombination, and Radiosensitizes S/G2-phase Cells*
Y. Lio
,
D. Schild
,
M. Brenneman
,
J. Redpath
,
David J. Chen
Journal of Biological Chemistry
2004
Corpus ID: 45136625
The highly conserved Rad51 protein plays an essential role in repairing DNA damage through homologous recombination. In…
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Highly Cited
2004
Highly Cited
2004
Domain mapping of the Rad51 paralog protein complexes.
K. A. Miller
,
D. Sawicka
,
D. Barsky
,
J. Albala
Nucleic Acids Research
2004
Corpus ID: 17825810
The five human Rad51 paralogs are suggested to play an important role in the maintenance of genome stability through their…
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2004
2004
Rad51C deficiency destabilizes XRCC3, impairs recombination and radiosensitizes S/G 2 -phase cells
Y. Lio
,
D. Schild
,
M. Brenneman
,
J. Redpath
,
David J. Chen
2004
Corpus ID: 5202976
The highly conserved Rad51 protein plays an essential role in repairing DNA damage through homologous recombination. In…
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Highly Cited
2002
Highly Cited
2002
Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells.
Nan Liu
,
D. Schild
,
M. Thelen
,
L. Thompson
Nucleic Acids Research
2002
Corpus ID: 45747808
Genetic studies in rodent and chicken mutant cell lines have suggested that Rad51 paralogs (XRCC2, XRCC3, Rad51B/Rad51L1, Rad51C…
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Highly Cited
2002
Highly Cited
2002
A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer.
S. Rafii
,
Paul O'Regan
,
+6 authors
A. Cox
Human Molecular Genetics
2002
Corpus ID: 14079660
An acquired genetic instability, resulting from the loss of some types of DNA repair, is an early event in the development of a…
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Highly Cited
2002
Highly Cited
2002
Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells.
C. Wiese
,
D. Collins
,
J. Albala
,
L. Thompson
,
A. Kronenberg
,
D. Schild
Nucleic Acids Research
2002
Corpus ID: 46067788
Homologous recombinational repair of DNA double-strand breaks and crosslinks in human cells is likely to require Rad51 and the…
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2002
2002
A potential role for the XRCC 2 R 188 H polymorphic site in DNA-damage repair and breast cancer
S. Rafii
,
Paul O'Regan
,
+6 authors
A. Cox
2002
Corpus ID: 113400328
An acquired genetic instability, resulting from the loss of some types of DNA repair, is an early event in the development of a…
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