Rad51B-Rad51C-Rad51D-XRCC2 complex

Known as: BCDX2 complex, BCDX2 complex location, Rad51B-Rad51C-Rad51D-XRCC2 complex location 
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof. [GOC:mah, PMID:16093548… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
012320012017

Papers overview

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2013
2013
The Rad51 paralogs are required for homologous recombination (HR) and the maintenance of genomic stability. The molecular… (More)
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2009
2009
The double-strand break (DSB) DNA repair pathway has been implicated in breast cancer (BC). RAD51 and its paralogs XRCC3 and… (More)
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2007
2007
In germ line cells, recombination is required for gene reassortment and proper chromosome segregation at meiosis, whereas in… (More)
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2006
2006
Homologous recombinational repair (HRR) restores chromatid breaks arising during DNA replication and prevents chromosomal… (More)
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Highly Cited
2006
Highly Cited
2006
DNA repair by homologous recombination is essential for preserving genomic integrity. The RAD51 paralogs (RAD51B, RAD51C, RAD51D… (More)
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2004
2004
The Rad51B, Rad51C, Rad51D and Xrcc2 proteins are Rad51 paralogs, and form a complex (BCDX2 complex) in mammalian cells. Mutant… (More)
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2004
2004
The highly conserved Rad51 protein plays an essential role in repairing DNA damage through homologous recombination. In… (More)
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2004
2004
The five human Rad51 paralogs are suggested to play an important role in the maintenance of genome stability through their… (More)
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2002
2002
Genetic studies in rodent and chicken mutant cell lines have suggested that Rad51 paralogs (XRCC2, XRCC3, Rad51B/Rad51L1, Rad51C… (More)
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2002
2002
Homologous recombinational repair of DNA double-strand breaks and crosslinks in human cells is likely to require Rad51 and the… (More)
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