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Rad51B-Rad51C-Rad51D-XRCC2 complex

Known as: BCDX2 complex, BCDX2 complex location, Rad51B-Rad51C-Rad51D-XRCC2 complex location 
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof. [GOC:mah, PMID:16093548… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
ABSTRACT The Rad51 paralogs are required for homologous recombination (HR) and the maintenance of genomic stability. The… Expand
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2010
2010
In mammals, there are five Rad51 paralogs that form two distinct complexes in vivo. One complex is composed of Rad51B-Rad51C… Expand
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Highly Cited
2007
Highly Cited
2007
In germ line cells, recombination is required for gene reassortment and proper chromosome segregation at meiosis, whereas in… Expand
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2007
2007
RAD51D is a homolog of the RAD51 protein, which is known to be an important component of the DNA repair pathway. A rare missense… Expand
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Highly Cited
2004
Highly Cited
2004
The highly conserved Rad51 protein plays an essential role in repairing DNA damage through homologous recombination. In… Expand
Highly Cited
2004
Highly Cited
2004
The five human Rad51 paralogs are suggested to play an important role in the maintenance of genome stability through their… Expand
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Highly Cited
2002
Highly Cited
2002
An acquired genetic instability, resulting from the loss of some types of DNA repair, is an early event in the development of a… Expand
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Highly Cited
2002
Highly Cited
2002
Genetic studies in rodent and chicken mutant cell lines have suggested that Rad51 paralogs (XRCC2, XRCC3, Rad51B/Rad51L1, Rad51C… Expand
Highly Cited
2002
Highly Cited
2002
Homologous recombinational repair of DNA double-strand breaks and crosslinks in human cells is likely to require Rad51 and the… Expand
2002
2002
An acquired genetic instability, resulting from the loss of some types of DNA repair, is an early event in the development of a… Expand
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