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RX 871024

Known as: RX-871024, RX871024 
National Institutes of Health

Papers overview

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2006
2006
RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.
2002
2002
Insulinotropic activity of the imidazoline derivative RX871024 in the diabetic GK rat.
The insulinotropic activity of the imidazoline derivative RX871024 was compared in pancreatic islets from nondiabetic Wistar rats… 
2001
2001
Phentolamine Inhibits Exocytosis of Glucagon by Gi2 Protein-dependent Activation of Calcineurin in Rat Pancreatic α-Cells*
Capacitance measurements were used to investigate the molecular mechanisms by which imidazoline compounds inhibit glucagon… 
2001
2001
The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function.
Effects of the imidazoline compound RX871024 on cytosolic free Ca(2+) concentration ([Ca(2+)]i) and insulin secretion in… 
1999
1999
Different Modes of Action of the Imidazoline Compound RX871024 in Pancreatic β‐Cells: Blocking of K+ Channels, Mobilization of Ca2+ from Endoplasmic Reticulum, and Interaction with Exocytotic…
ABSTRACT: The imidazoline compound RX871024 glucose‐dependently potentiates the release of insulin in pancreatic islets and… 
1999
1999
Multiple effector pathways regulate the insulin secretory response to the imidazoline RX871024 in isolated rat pancreatic islets
When isolated rat islets were cultured for 18 h prior to use, the putative imidazoline binding site ligand, RX871024 caused a… 
1998
1998
Signaling and sites of interaction for RX-871024 and sulfonylurea in the stimulation of insulin release.
The objective of this study was to compare effects of RX-871024, a compound with imidazoline structure, and the sulfonylurea… 
1998
1998
RX871024 Induces Ca2+ Mobilization From Thapsigargin-Sensitive Stores in Mouse Pancreatic β-Cells
The effects of RX871024, a compound with an imidazoline structure, on cytoplasmic-free Ca2+ concentration ([Ca2+]i) in mouse… 
1998
1998
Effects of imidazoline derivative RX871024 on insulin, glucagon, and somatostatin secretion from isolated perfused rat pancreas.
The effects of the imidazoline compound RX871024 on arginine-induced insulin, glucagon, and somatostatin secretion in the… 
1998
1998
Effector systems involved in the insulin secretory responses to efaroxan and RX871024 in rat islets of Langerhans.
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