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RWJ 671818
Known as:
RWJ-671818
, RWJ671818
National Institutes of Health
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2010
2010
Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine…
Tianbao Lu
,
Thomas P. Markotan
,
+12 authors
M. Player
Journal of Medicinal Chemistry
2010
Corpus ID: 8008292
We have identified RWJ-671818 (8) as a novel, low molecular weight, orally active inhibitor of human alpha-thrombin (K(i) = 1.3…
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