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Patients with cirrhosis have an increased risk of developing liver cancer and a higher rate of mortality. Cirrhosis… Expand BACKGROUND
Semi-synthetic oleanane triterpenoid antioxidant inflammation modulators (tpAIMs) are small molecules that interact… Expand Synthetic triterpenoids are antioxidant inflammation modulators (AIMs) that exhibit broad anticancer activity. AIMs bind to KEAP1… Expand Bardoxolone methyl and related triterpenoids are well tolerated and efficacious in numerous animal models potentially relevant to… Expand the results of the 52-wk Phase IIb Bardoxolone Methyl Treatment: Renal Function in CKD/Type 2 Diabetes (BEAM) study that were… Expand