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RSPO1 gene

Known as: RSPO, R-spondin 1, RSPO1 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Novel Insights into Gastric Cancer: Methylation of R-spondins and Regulation of LGR5 by SP1
Recently, it was shown that leucine-rich repeat-containing receptor 5 (LGR5)–expressing stem cells are the cellular origin of… 
2016
2016
MYC and PVT1 synergize to regulate RSPO1 levels in breast cancer
ABSTRACT Copy number gain of the 8q24 region including the v-myc avian myelocytomatosis viral oncogene homolog (MYC) oncogene has… 
2015
2015
Engineering High-Potency R-spondin Adult Stem Cell Growth Factors
Secreted R-spondin proteins (RSPOs1–4) function as adult stem cell growth factors by potentiating Wnt signaling. Simultaneous… 
2015
2015
Pancreatic CSCs and microenvironment
Pancreatic ductal adenocarcinoma (PDAC) is the most common malignant neoplasm of the pancreas and presents with dismal prognosis… 
2012
2012
Modulating WNT receptor turnover for tissue repair
New mechanistic insight into the regulation of WNT signaling supports efforts to target this pathway in adult stem cells for… 
2011
2011
F-spondin inhibits migration and differentiation of osteoclastic precursors.
BACKGROUND Clinically, severe cemental resorption is a rare consequence of periodontitis, although alveolar bone resorption by… 
2010
2010
F‐spondin regulates chondrocyte terminal differentiation and endochondral bone formation
This study examines the role of F‐spondin, an extracellular matrix protein of osteoarthritic cartilage, during chondrocyte… 
2009
2009
Effects of process parameters on the properties of biocompatible ibuprofen-loaded microcapsules.
2009
2009
Goat RSPO1 over-expression rescues sex-reversal in Rspo1-knockout XX mice but does not perturb testis differentiation in XY or sex-reversed XX mice
RSPO1 is a newly discovered gene involved in sex differentiation. Two goat BAC clones encompassing the RSPO1 gene (gRSPO1) were… 
Review
2008
Review
2008
Mutations in the RSPO1 Coding Region Are Not the Main Cause of Canine SRY-Negative XX Sex Reversal in Several Breeds
This report details a case of SRY-negative XX sex reversal in a mixed breed dog and surveys affected dogs of several breeds for… 
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