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RS 43285

Known as: 43285, RS, RS-43285, RS43285 
National Institutes of Health

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1 relation

Broader (1)

ranolazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
SUSTAINED RELEASE RANOLANOLAZINE FORMULATION
  • 2017
  • Corpus ID: 54936047
Allely MC. Alps B.J. Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion, Br… 
Review
2006
Review
2006
Ranolazine:an Antiischemic Drug with a Novel Mechanism of Action
It has been generally accepted that the primary mechanism of action of antianginal drugs is the improvement of the myocardial… 
2004
2004
Ranolazine (RS-43285): A preliminary study of a new anti-anginal agent with selective effect on ischaemic myocardium
SummaryRanolazine (RS-43285) has been shown to possess significant anti-ischaemic properties in a canine model of reversible… 
1995
1995
The antianginal agent ranolazine is a weak inhibitor of the respiratory complex I, but with greater potency in broken or uncoupled than in coupled mitochondria.
1995
1995
The characterization of the metabolites of ranolazine in man by liquid chromatography mass spectrometry.
The metabolism of ranolazine (RS-43285) or (+)N-(2,6-dimethylphenyl)-4[2-hydroxy-3-(2-methoxyphenoxy)-propyl]-1- piperazine… 
Highly Cited
1994
Highly Cited
1994
Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart.
OBJECTIVE The aim was to examine the putative cardioprotective effects of the novel antianginal agent, ranolazine, using an… 
Highly Cited
1992
Highly Cited
1992
Effects of a New Metabolic Modulator, Ranolazine, on Exercise Tolerance in Angina Pectoris Patients Treated with β‐Blocker or Diltiazem
Summary: Ranolazine (RS 43285) is a new piperazine derivative with anti-ischemic properties attributed to a modulation of… 
Highly Cited
1990
Highly Cited
1990
Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion
In control anaesthetized baboons subjected to 30 min occlusion of the left anterior descending coronary artery, followed by 5.5 h… 
1987
1987
Rs-43285 (Syntex) A Preliminary Study of A Unique Anti-Anginal Agent
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