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RPX7009

National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Boronic AcidsHeterocyclic Compounds, 1-Ring

Papers overview

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2016
2016
Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors
Abstractβ-Lactamases are bacterial enzymes conferring resistance to β-lactam antibiotics in clinically-relevant pathogens, and… 
2015
2015
Meropenem-RPX 7009 Concentrations in Plasma , Epithelial Lining Fluid , and Alveolar Macrophages of Healthy Adult Subjects
The steady-state concentrations of meropenem and the -lactamase inhibitor RPX7009 in plasma, epithelial lining fluid (ELF), and… 
2014
2014
401A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the Beta-lactamase inhibitor RPX7009 Alone, Meropenem Alone, and both in Combination (Carbavance) TID for 7 days in Healthy…
2013
2013
In Vitro Activity of Biapenem plus RPX7009, a Carbapenem Combined with a Serine β-Lactamase Inhibitor, against Anaerobic Bacteria
ABSTRACT Biapenem is a carbapenem being developed in combination with RPX7009, a new inhibitor of serine β-lactamases. Biapenem… 
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