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RPA bicyclam

National Institutes of Health

Papers overview

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2020
2020
Expression of the chemokine receptor chemokine C-X-C motif receptor 4 (CXCR4) plays an important role in cancer metastasis, in… 
2018
2018
Positron emission tomography (PET) imaging is a non-invasive modality that permits the characterisation of biological processes… 
2014
2014
For instance,one of the metallocyclam units in the metalloxylyl-bicy-clam is folded with Cis-V configuration, where the… 
2011
2011
Background: The development of distant metastasis is associated with poor outcome in patients with colorectal cancer (CRC). The… 
Highly Cited
2009
Highly Cited
2009
The bicyclam AMD3100 is known as a small synthetic inhibitor of the CXCL12-binding chemokine receptor CXCR4. Here, we show that… 
Highly Cited
2005
Highly Cited
2005
Highly Cited
2005
Highly Cited
2005
The macrocyclic antiviral drug xylyl-bicyclam blocks entry of HIV into cells by targeting the CXCR4 coreceptor, a seven-helix… 
Highly Cited
2002
Highly Cited
2002
As platforms for the design of metal-based therapeutic and diagnostic agents, macrocycles are rigid enough to provide strong… 
Highly Cited
2001
Highly Cited
2001
The bicyclam AMD3100 is a highly potent and selective CXCR4 antagonist with strong antiviral activity against human… 
Highly Cited
1999
Highly Cited
1999
ABSTRACT The emergence of X4 human immunodeficiency virus type 1 (HIV-1) strains in HIV-1-infected individuals has been…