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RPA bicyclam

 
National Institutes of Health

Papers overview

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2020
2020
Expression of the chemokine receptor chemokine C-X-C motif receptor 4 (CXCR4) plays an important role in cancer metastasis, in… Expand
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2018
2018
Positron emission tomography (PET) imaging is a non-invasive modality that permits the characterisation of biological processes… Expand
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2014
2014
For instance,one of the metallocyclam units in the metalloxylyl-bicy-clam is folded with Cis-V configuration, where the… Expand
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2011
2011
Background: The development of distant metastasis is associated with poor outcome in patients with colorectal cancer (CRC). The… Expand
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Highly Cited
2009
Highly Cited
2009
The bicyclam AMD3100 is known as a small synthetic inhibitor of the CXCL12-binding chemokine receptor CXCR4. Here, we show that… Expand
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Highly Cited
2005
Highly Cited
2005
The chemokine receptors CCR5 and CXCR4 function as coreceptors for human immunodeficiency virus (HIV) and are attractive targets… Expand
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2005
2005
The macrocyclic antiviral drug xylyl-bicyclam blocks entry of HIV into cells by targeting the CXCR4 coreceptor, a seven-helix… Expand
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2002
2002
As platforms for the design of metal-based therapeutic and diagnostic agents, macrocycles are rigid enough to provide strong… Expand
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2001
2001
The bicyclam AMD3100 is a highly potent and selective CXCR4 antagonist with strong antiviral activity against human… Expand
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1999
1999
The emergence of X4 human immunodeficiency virus type 1 (HIV-1) strains in HIV-1-infected individuals has been associated with… Expand
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