FAQ

RPA bicyclam

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
0119982018

Related topics

Related topics

1 relation
JM 3100

Related mentions per year

Related mentions per year

1994-2018
1990200020102020
RPA bicyclam
JM 3100

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Rapid visual detection of Mycobacterium avium subsp. paratuberculosis by recombinase polymerase amplification combined with a lateral flow dipstick
Paratuberculosis (Johne's disease) is a chronic debilitating disease of domestic and wild ruminants. However, widespread point-of… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2011
2011
A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.
BACKGROUND The development of distant metastasis is associated with poor outcome in patients with colorectal cancer (CRC). The… (More)
Is this relevant?
2010
2010
Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4…
Bis-tetraazamacrocycles such as the bicyclam AMD3100 (1) are a class of potent and selective anti-HIV-1 agents that inhibit virus… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
2005
2005
Protein recognition of macrocycles: binding of anti-HIV metallocyclams to lysozyme.
The macrocyclic antiviral drug xylyl-bicyclam blocks entry of HIV into cells by targeting the CXCR4 coreceptor, a seven-helix… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
2002
2002
Structure and dynamics of metallomacrocycles: recognition of zinc xylyl-bicyclam by an HIV coreceptor.
As platforms for the design of metal-based therapeutic and diagnostic agents, macrocycles are rigid enough to provide strong… (More)
Is this relevant?
2001
2001
Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.
The bicyclam AMD3100 is a highly potent and selective CXCR4 antagonist with strong antiviral activity against human… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1999
1999
Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor.
Bicyclams represent a novel class of selective anti-HIV inhibitors with potent activity against T-cell tropic strains of HIV. The… (More)
  • table 1
  • figure 1
  • table 2
  • figure 3
  • figure 4
Is this relevant?
1998
1998
Determinants for sensitivity of human immunodeficiency virus coreceptor CXCR4 to the bicyclam AMD3100.
The bicyclam AMD3100 is a potent and selective inhibitor of the replication of human immunodeficiency virus type 1 and type 2… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?