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RP 48740

Known as: 48740 RP, 48740RP, RP-48740 
National Institutes of Health

Papers overview

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2004
2004
Inhibition of ex-vivo PAF-induced platelet aggregation by the PAF-antagonist RP 48740: relationship to plasma concentrations in healthy volunteers
SummaryRP 48740, 3-(3-pyridyl)-1H,3H-pyrrolo [1,2-c] thiazole-7-carboxamide, a specific competitive PAF-receptor antagonist in… 
1994
1994
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
1991
1991
Inhibitory effects of a platelet activating factor-antagonist 48740RP in cyclosporin-induced nephrotoxicity in the rat as assessed by renal glutathione metabolism parameters.
Cyclosporin A (CsA) is a potent immunosuppressive agent that has improved renal allograft survival. However, together with its… 
1990
1990
PROLONGED SURVIVAL OF RENAL TRANSPLANTS IN NONIMMUNIZED AND HYPERIMMUNIZED RATS RECEIVING A PLATELET‐ACTIVATING FACTOR ANTAGONIST
A potent platelet-activating factor (PAF) antagonist, RP 48740, was tested for its ability to delay acute and accelerated… 
1989
1989
Antagonism of Paf‐induced oedema formation in rabbit skin: a comparison of different antagonists
1 Eight platelet activating factor (Paf) antagonists were evaluated as inhibitors of oedema formation in rabbit skin induced by… 
1987
1987
Interactions between local inflammatory and systemic haematological effects of PAF-acether in the rat.
1987
1987
Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay.
1987
1987
Desensitization and antagonism of rat polymorphonuclear leukocytes stimulated with PAF acether.
1987
1987
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets
Four chemically distinct PAF-acether antagonists were used to test the hypothesis that the cyclooxygenase and ADP-independent… 
1986
1986
Effects of PAF-acether and structural analogues on platelet activation and bronchoconstriction in guinea-pigs.
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