RNA splicing, via transesterification reactions with guanosine as nucleophile

Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile. [GOC:krc, PMID:11377794]
National Institutes of Health

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Topic mentions per year

1986-2017
01219862017

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2017
2017
The potassium salt of the boron-centred nucleophile B(CN)32- (1) readily reacts with perfluorinated arenes, such as… (More)
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2014
2014
The very strong reducing capabilities of the boryllithium nucleophile (THF)2Li{B(NDippCH)2} (1, Dipp = 2,6-iPr2C6H3) render… (More)
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2013
2013
We herein report results obtained from an integrated experimental and theoretical study on aromatic nucleophilic substitution (S… (More)
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Review
2011
Review
2011
Targeting cancer with small molecule irreversible inhibitors of kinases represents an emerging challenge in drug discovery… (More)
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2009
2009
Highly regio- and enantioselective iridium-catalyzed N-allylations of benzimidazoles, imidazoles, and purines have been developed… (More)
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2008
2008
Nucleophile (11)C/ (14)C [ k (11)/ k (14)] and secondary alpha-deuterium [( k H/ k D) alpha] kinetic isotope effects (KIEs) were… (More)
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2005
2005
[reaction: see text] A new synthesis of enantiopure 3,3-disubstituted oxindoles by stereoselective Mukaiyama aldol reaction of 3… (More)
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2004
2004
Cytochrome P450 BM-3 variant 139-3 is highly active in the hydroxylation of alkanes and fatty acids (AGlieder, ET Farinas, and FH… (More)
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1986
1986
Rate constants for the reactions of substituted quinuclidines with pnitrophenyl phosphate, 2,4-dinitrophenyl phosphate, 2,4… (More)
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