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RNA splicing, via transesterification reactions with guanosine as nucleophile

Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile. [GOC:krc, PMID:11377794]
National Institutes of Health

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2018
2018
Chemoselective Benzylation of Aldehydes Using Lewis Base Activated Boronate Nucleophiles.
A benzylation of aldehydes using primary and secondary benzylboronic acid pinacol esters is reported. Activation of the boronic… 
Review
2012
Review
2012
Pd-Catalyzed Telomerization of 1,3-Dienes with Multifunctional Renewable Substrates: Versatile Routes for the Valorization of Biomass-Derived Platform Molecules
The dimerization of 1,3-dienes (e.g. butadiene) with the addition of a protic nucleophile (e.g. methanol) yields 2,7-octadienyl… 
Highly Cited
2009
Highly Cited
2009
Regio- and enantioselective N-allylations of imidazole, benzimidazole, and purine heterocycles catalyzed by single-component metallacyclic iridium complexes.
Highly regio- and enantioselective iridium-catalyzed N-allylations of benzimidazoles, imidazoles, and purines have been developed… 
2009
2009
Selective surface chemistry of allyl alcohol and allyl aldehyde on Si(1 0 0)2×1: Competition of [2 + 2] CC cycloaddition with O–H dissociation and with [2 + 2] CO cycloaddition in bifunctional…
2009
2009
Réactivité des noyaux indoliques vis-à-vis des nitrones alpha-chirales : application à la synthèse multi-étapes de dérives 11-amines de l'azaelliptitoxine
L'azaelliptitoxine, molecule antitumorale, a ete elaboree par modelisation moleculaire a partir des structures de l'ellipticine… 
2008
2008
Dual macrolactonization/pyran-hemiketal formation via acylketenes: applications to the synthesis of (-)-callipeltoside A and a lyngbyaloside B model system.
Thermal generation of acylketenes in diol-containing substrates results in dual macrocyclization/pyran-hemiketal formation. This… 
2007
2007
Methodology for the preparation of 2-argininylbenzothiazole.
An efficient process to produce kilogram quantities of a key argininylbenzo[d]thiazole intermediate was developed for the… 
2006
2006
Studies on the mechanism of action of prekinamycin, a member of the diazoparaquinone family of natural products: evidence for both sp2 radical and orthoquinonemethide intermediates.
The putative reductive activation chemistry of the diazoparaquinone antibiotics was modeled with Bu(3)Sn-H and prekinamycin… 
2004
2004
Synthèse de beta-lactames monocycliques fonctionnalisés, précurseurs d'antibiotiques (carbapénèmes)
Les carbapenemes occupent actuellement une place centrale dans la lutte contre les bacteries resistantes aux antibiotiques… 
1997
1997
Etude didactique et épistémologique de l'enseignement expérimental en chimie : apprentissage de la démarche scientifique au laboratoire sur le thème de la substitution nucléophile d'halogénures d…
La recherche presentee ici concerne l'enseignement experimental en chimie considere comme une forme d'apprentissage relevant des… 
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