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RNA repair
Any process that results in the repair of damaged RNA. [PMID:11000254, PMID:11070075, UniProtKB-KW:KW-0692]
National Institutes of Health
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2018
2018
Genetic bypass of essential RNA repair enzymes in budding yeast
P. Cherry
,
L. K. White
,
Kerri T. York
,
J. Hesselberth
RNA: A publication of the RNA Society
2018
Corpus ID: 3699458
RNA repair enzymes catalyze rejoining of an RNA molecule after cleavage of phosphodiester linkages. RNA repair in budding yeast…
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2014
2014
Design and Characterization of a Twin Ribozyme for Potential Repair of a Deletion Mutation within the Oncogenic CTNNB1‐ΔS45 mRNA
Darko Balke
,
Irene Zieten
,
A. Strahl
,
O. Müller
,
S. Müller
ChemMedChem
2014
Corpus ID: 40213007
RNA repair is an emerging strategy for gene therapy. Conventional gene therapy typically relies on the addition of the corrected…
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Review
2014
Review
2014
The Current Progress of RNA Repair
Li We
2014
Corpus ID: 88393646
The mechanism of the organism to repair DNA damage has been studied in reasonable detail.In contrast,the agents of damage to DNA…
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2012
2012
Probing the substrate specificity of the bacterial Pnkp/Hen1 RNA repair system using synthetic RNAs.
Can Zhang
,
C. Chan
,
Pei Wang
,
Raven H. Huang
RNA: A publication of the RNA Society
2012
Corpus ID: 38717952
Ribotoxins cleave essential RNAs involved in protein synthesis as a strategy for cell killing. RNA repair systems exist in nature…
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2010
2010
Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette.
R. Jain
,
S. Shuman
RNA: A publication of the RNA Society
2010
Corpus ID: 6134829
Hen1 is an RNA ribose 2'-O-methyltransferase that modifies the 3' terminal nucleoside of eukaryal small regulatory RNAs. Here, we…
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2007
2007
Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme
Niroshika M Keppetipola
,
J. Nandakumar
,
S. Shuman
Nucleic Acids Research
2007
Corpus ID: 2509726
Programmed RNA breakage is an emerging theme underlying cellular responses to stress, virus infection and defense against foreign…
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2004
2004
Characterization of Polynucleotide Kinase/Phosphatase Enzymes from Mycobacteriophages Omega and Cjw1 and Vibriophage KVP40*
Hui Zhu
,
Shenmin Yin
,
S. Shuman
Journal of Biological Chemistry
2004
Corpus ID: 31918214
Coliphage T4 Pnkp is a bifunctional polynucleotide 5′-kinase/3′-phosphatase that catalyzes the end-healing steps of a RNA repair…
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2003
2003
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
J. Byun
,
N. Lan
,
Meredith B. Long
,
B. Sullenger
RNA: A publication of the RNA Society
2003
Corpus ID: 34499663
Previously we demonstrated that a group I ribozyme can perform trans-splicing to repair sickle beta-globin transcripts upon…
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2001
2001
Research Corrigenda
Nature Biotechnology
2001
Corpus ID: 196627782
Spliceosome-mediated RNA trans-splicing as a tool for gene therapy M. Puttaraju, Sharon F. Jamison, S. Gary Mansfield, Mariano A…
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2000
2000
Enhancing RNA repair efficiency by combining trans-splicing ribozymes that recognize different accessible sites on a target RNA.
N. Lan
,
B. Rooney
,
S. W. Lee
,
R. Howrey
,
C. Smith
,
B. Sullenger
Molecular Therapy
2000
Corpus ID: 31662349
Recent reports have demonstrated that trans-splicing ribozymes can be employed to repair mutant RNAs. One key factor that…
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