RNA-Binding Protein Musashi Homolog 1

Known as: Musashi 1, Musashi-1 
RNA-binding protein Musashi homolog 1 (362 aa, ~39 kDa) is encoded by the human MSI1 gene. This protein is involved in translational modulation… (More)
National Institutes of Health

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Homo sapiensMSI1 geneRNA BindingTranslational Regulation

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Highly Cited
2008
Highly Cited
2008
Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.
BACKGROUND & AIMS In the gut, tumorigenesis is thought to arise from the stem cell population located near the base of intestinal… (More)
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Highly Cited
2006
Highly Cited
2006
The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1.
RNA-binding proteins regulate cell fate decisions during nervous system development. The Msi family of RNA-binding proteins is… (More)
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Review
2005
Review
2005
Function of RNA-binding protein Musashi-1 in stem cells.
Musashi is an evolutionarily conserved family of RNA-binding proteins that is preferentially expressed in the nervous system. The… (More)
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Highly Cited
2003
Highly Cited
2003
Identification of a putative intestinal stem cell and early lineage marker; musashi-1.
There are few reliable markers for adult stem cells and none for those of the intestinal epithelium. Previously, indirect… (More)
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Highly Cited
2003
Highly Cited
2003
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine.
Musashi-1, a neural RNA-binding protein, is important for maintaining neural stem cells. Both Musashi-1 and Hes1, a… (More)
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Highly Cited
2003
Highly Cited
2003
Cancerous stem cells can arise from pediatric brain tumors.
Pediatric brain tumors are significant causes of morbidity and mortality. It has been hypothesized that they derive from self… (More)
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Highly Cited
2002
Highly Cited
2002
RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.
Homologues of the Musashi family of RNA-binding proteins are evolutionarily conserved across species. In mammals, two members of… (More)
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Highly Cited
2001
Highly Cited
2001
The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA.
Musashi1 (Msi1) is an RNA-binding protein that is highly expressed in neural progenitor cells, including neural stem cells. In… (More)
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Highly Cited
2001
Highly Cited
2001
Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS.
Musashi1 (Msi1) is a mammalian neural RNA-binding protein highly enriched in neural precursor cells that are capable of… (More)
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Highly Cited
1996
Highly Cited
1996
Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell.
There is increasing interest in the role of RNA-binding proteins during neural development. Drosophila Musashi is one of the… (More)
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