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RHOBTB2 gene

Known as: DBC2, RHO-RELATED BTB DOMAIN-CONTAINING PROTEIN 2, KIAA0717 
National Institutes of Health

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RHOBTB3 gene

Papers overview

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2015
2015
RhoBTB2 (DBC2) functions as a multifunctional tumor suppressor in thyroid cancer cells via mitochondrial apoptotic pathway.
Thyroid cancer is the most common endocrine malignancy worldwide. Tumor suppressor gene RhoBTB2 (also known as Deleted in Breast… 
2014
2014
RhoBTB2 gene in breast cancer is silenced by promoter methylation.
Mutation analysis in breast cancer has failed to explain the inactivation of RhoBTB2, a candidate breast cancer tumor suppressor… 
2014
2014
The mutation of DBC2 in breast cancer patients from the Han ethnic group in Eastern China.
2012
2012
Evaluation of Methylation Status in the 5'UTR Promoter Region of the DBC2 Gene as a Biomarker in Sporadic Breast Cancer
Objective: Breast cancer is one of the most common malignancies in women worldwide. It is caused by a number of genetic and… 
2012
2012
Identifying neuromuscular abnormalities in ThoBTB3 deficient mice, using the phenotypic assessment protocol - SHIRPA
RhoBTBs proteins are atypical Rho GTPase involved in tumor regulation. This subfamily consists in three isoforms: RhoBTB1… 
2010
2010
RhoBTB2 (DBC2) comes of age as a multifunctional tumor suppressor
Commentary to: Ectopic expression of RhoBTB2 inhibits migration and invasion of human breast cancer cells Li-Jun Ling, Chao Lu… 
2010
2010
DBC2 negatively regulates the proliferation of breast cancer cells and induces apoptosis
Objective To gain insight into the biological function of DBC2 in MDA-MB-435S breast cancer cell line in vitro.Methods Transient… 
2010
2010
Construction of recombinant type 5 adenovirus expressing human DBC2 gene in bladder cancer cells
ObjectiveThe aim of the study was to construct recombinant type 5 adenovirus expressing the human DBC2 (deleted in breast cancer… 
2007
2007
Mutation analysis of the DBC2 gene in sporadic and familial breast cancer
The expression of the recently identified tumor suppressor gene, DBC2 (Deleted in Breast Cancer 2), is frequently extinguished in… 
2006
2006
DBC2 is essential for transporting vesicular stomatitis virus glycoprotein.
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