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RHEB gene

Known as: RHEB2, FORMERLY, Ras homolog enriched in brain, RAS HOMOLOG ENRICHED IN BRAIN 2, FORMERLY 
This gene plays a role in the regulation of MTORC1-dependent signaling.
National Institutes of Health

Related topics

Related topics

7 relations
GTP BindingHomo sapiensRHEBL1 geneRHEBP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Rheb (Ras Homolog Enriched in Brain 1) Deficiency in Mature Macrophages Prevents Atherosclerosis by Repressing Macrophage Proliferation, Inflammation, and Lipid Uptake.
OBJECTIVE Macrophage foam cell formation is an important process in atherosclerotic plaque development. The small GTPase Rheb… 
2018
2018
Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells.
2018
2018
An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation
RHEB is a unique member of the RAS superfamily of small GTPases expressed in all tissues and conserved from yeast to humans… 
2018
2018
Overexpression of RHEB is associated with metastasis and poor prognosis in hepatocellular carcinoma.
Aberrant expression of Ras homolog enriched in brain (RHEB) has been observed in a variety of cancer tissues and is closely… 
2012
2012
Pathophysiological Implications in Obesity and Metabolic Syndrome Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia :
Sebastiano Sciarretta, Peiyong Zhai, Dan Shao, Yasuhiro Maejima, Jeffrey Robbins, Pathophysiological Implications in Obesity and… 
2012
2012
Expressional Difference of RHEB, HDAC1, and WEE1 Proteins in the Stromal Tumors of the Breast and Their Significance in Tumorigenesis
Background Fibroadenoma (FA) and phyllodes tumor (PT) are stromal tumors of breast and are histologically similar. There are no… 
2012
2012
Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2‐null ELT3 cells: A potential treatment for lymphangioleiomyomatosis
The small GTPase proteins, Ras and Rheb, serve as molecular switches regulating cell proliferation, differentiation and apoptosis… 
2006
2006
Measurements of TSC2 GAP activity toward Rheb.
2006
2006
Year : 2003 Insulin activation of Rheb , a mediator of mTOR / S 6 K / 4 EBP signaling , is inhibited by TSC 1 and 2
Tumor suppressor genes evolved as negative effectors of mitogen and nutrient signaling pathways, such that mutations in these… 
2001
2001
Characterization of Rheb functions using yeast and mammalian systems.
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