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RGFP966

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
0246820132017

Related topics

Related topics

2 relations

Broader (2)

AcrylamidesPhenylenediamines

Related mentions per year

Related mentions per year

1941-2018
19401960198020002020
RGFP966
Phenylenediamines
Acrylamides

Papers overview

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2017
2017
HDAC3 Inhibitor RGFP966 Modulates Neuronal Memory for Vocal Communication Signals in a Songbird Model
Epigenetic mechanisms that modify chromatin conformation have recently been under investigation for their contributions to… (More)
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2016
2016
HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity
The increasing number of patients suffering from chronic obstructive pulmonary disease (COPD) represents a major and increasing… (More)
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2016
2016
Inhibition of Histone Deacetylase 3 Restores Amyloid-β Oligomer-Induced Plasticity Deficit in Hippocampal CA1 Pyramidal Neurons.
Neurodegenerative diseases such as Alzheimer's disease (AD) are associated with alterations in epigenetic factors leading to… (More)
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2015
2015
Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation.
Research over the past decade indicates a novel role for epigenetic mechanisms in memory formation. Of particular interest is… (More)
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2015
2015
Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue
Histone deacetylases (HDACs) are promising therapeutic targets for neurological and psychiatric disorders that impact cognitive… (More)
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2015
2015
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Histone deacetylase (HDAC) inhibitors (HDACis) have demonstrated activity in hematological and solid malignancies. Vorinostat… (More)
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2015
2015
TGF-β induces miR-30d down-regulation and podocyte injury through Smad2/3 and HDAC3-associated transcriptional repression
The microRNA-30 family plays important roles in maintaining kidney homeostasis. Patients with focal segmental glomerulosclerosis… (More)
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2015
2015
The Class I HDAC inhibitor RGFP963 enhances consolidation of cued fear extinction.
Evidence indicates that broad, nonspecific histone deacetylase (HDAC) inhibition enhances learning and memory, however, the… (More)
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Highly Cited
2013
Highly Cited
2013
HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner.
Nonspecific histone deacetylase (HDAC) inhibition has been shown to facilitate the extinction of drug-seeking behavior in a… (More)
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2013
2013
Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma
Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and… (More)
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