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RGFP966

 
National Institutes of Health

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2 relations

Broader (2)

AcrylamidesPhenylenediamines

Papers overview

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2017
2017
HDAC3 Inhibitor RGFP966 Modulates Neuronal Memory for Vocal Communication Signals in a Songbird Model
Epigenetic mechanisms that modify chromatin conformation have recently been under investigation for their contributions to… Expand
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2017
2017
Inhibition of HDAC3 prevents diabetic cardiomyopathy in OVE26 mice via epigenetic regulation of DUSP5-ERK1/2 pathway.
Inhibition of total histone deacetylases (HDACs) was phenomenally associated with the prevention of diabetic cardiomyopathy (DCM… Expand
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2016
2016
HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity
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2016
2016
The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice
An important epigenetic modification in Huntington's disease (HD) research is histone acetylation, which is regulated by histone… Expand
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2016
2016
Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats
Brain ischemic preconditioning (PC) provides vital insights into the endogenous protection against stroke. Genomic and epigenetic… Expand
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2015
2015
Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation
Research over the past decade indicates a novel role for epigenetic mechanisms in memory formation. Of particular interest is… Expand
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2015
2015
Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue
Histone deacetylases (HDACs) are promising therapeutic targets for neurological and psychiatric disorders that impact cognitive… Expand
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2015
2015
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Histone deacetylase (HDAC) inhibitors (HDACis) have demonstrated activity in hematological and solid malignancies. Vorinostat… Expand
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Highly Cited
2013
Highly Cited
2013
HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner
Nonspecific histone deacetylase (HDAC) inhibition has been shown to facilitate the extinction of drug-seeking behavior in a… Expand
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2013
2013
Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma
Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and… Expand
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