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RFNG gene

Known as: RADICAL FRINGE, RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, RFNG 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
012319962018

Papers overview

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2016
2016
Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development.
Lunatic, Manic, and Radical Fringe (LFNG, MFNG, and RFNG) are N-acetylglucosaminyltransferases that modify Notch receptors and… (More)
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2015
2015
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia
Frontotemporal dementia (FTD) is the second most prevalent form of early onset dementia after Alzheimer's disease (AD). We… (More)
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2012
2012
Fringe Controls Naïve CD4+T Cells Differentiation through Modulating Notch Signaling in Asthmatic Rat Models
The ability of Notch signaling to regulate T helper cell development and differentiation has been widely accepted. Fringe, O… (More)
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2009
2009
Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain.
Tight regulation of Notch pathway signaling is important in many aspects of embryonic development. Notch signaling can be… (More)
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2009
2009
MFng is dispensable for mouse pancreas development and function.
Notch signaling regulates pancreatic cell differentiation, and mutations of various Notch signaling components result in… (More)
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2004
2004
Sequence and embryonic expression of three zebrafish fringe genes: lunatic fringe, radical fringe, and manic fringe.
Drosophila fringe and its homologues in vertebrates code for glycosyltransferases that modify Notch, altering the sensitivity of… (More)
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2002
2002
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice.
The Notch signaling pathway is important in regulating formation and anterior-posterior patterning of somites in vertebrate… (More)
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1999
1999
Genomic structure, mapping, and expression analysis of the mammalian Lunatic, Manic, and Radical fringe genes
The three members of the mammalian fringe gene family, Manic fringe (Mfng), Radical fringe (Rfng), and Lunatic fringe (Lfng… (More)
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1999
1999
Limbs move beyond the Radical fringe
The fringe genes and the Notch signalling pathway are important in limb development in vertebrates and in Drosophila,helping to… (More)
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1996
1996
The secreted product of Xenopus gene lunatic Fringe, a vertebrate signaling molecule.
Signaling molecules are essential for vertebrate embryonic development. Here, two Xenopus homologs of the Drosophila gene fringe… (More)
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