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RASGRF1 wt Allele

Known as: RAS-GRF1, GNRP, Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 wt Allele 
Human RASGRF1 wild type allele is located in the vicinity of 15q24 and is approximately 129 kb in length. This allele, which encodes guanine… Expand
National Institutes of Health

Related topics

Related topics

9 relations
15q24CDC25 and CHK1 Regulatory PathwayG2-M Cell Cycle CheckpointHomo sapiens
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Broader (1)

RASGRF1 gene

Papers overview

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2019
2019
Expression of Arabidopsis WEE1 in tobacco induces unexpected morphological and developmental changes
WEE1 regulates the cell cycle by inactivating cyclin dependent protein kinases (CDKs) via phosphorylation. In yeast and animal… Expand
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Highly Cited
2009
Highly Cited
2009
Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine
BACKGROUND Ras-extracellular signal-regulated kinase (Ras-ERK) signaling is central to the molecular machinery underlying… Expand
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Highly Cited
2006
Highly Cited
2006
Distinct Roles for Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) and Ras-GRF2 in the Induction of Long-Term Potentiation and Long-Term Depression
NMDA-type glutamate receptors (NMDARs) contribute to many forms of long-term potentiation (LTP) and long-term depression (LTD… Expand
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2005
2005
Cell Divisions in the Drosophila Embryonic Mesoderm Are Repressed via Posttranscriptional Regulation of string/cdc25 by HOW
BACKGROUND Cell-cycle progression is tightly regulated during embryonic development. In the Drosophila early embryo, the levels… Expand
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Highly Cited
2001
Highly Cited
2001
Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1)
Previous results have suggested that the Ras signaling pathway is involved in learning and memory. Ras is activated by nucleotide… Expand
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1997
1997
Identification of a dominant-negative mutation in the yeast CDC25 guanine nucleotide exchange factor for Ras
In previous studies we changed five conserved amino acid residues in the catalytic domain of the yeast Ras-specific guanine… Expand
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1996
1996
The kinetics of the B cyclin p56cdc13 and the phosphatase p80cdc25 during the cell cycle of the fission yeast Schizosaccharomyces pombe.
The levels of the B cyclin p56cdc13 and the phosphatase p80cdc25 have been followed in selection-synchronised cultures of… Expand
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1993
1993
Saccharomyces cerevisiae CDC25 (1028-1589) is a guanine nucleotide releasing factor for mammalian ras proteins and is oncogenic in NIH3T3 cells.
The best characterized yeast guanine nucleotide releasing factor is CDC25, which acts on RAS and thereby stimulates cAMP… Expand
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1993
1993
Identification of a human guanine nucleotide-releasing factor (H-GRF55) specific for Ras proteins.
A critical step in the activation of cellular Ras is the release of bound GDP. Oligonucleotide primers derived from a mouse cDNA… Expand
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1990
1990
The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, addition of glucose to cells grown under glucose-derepressed conditions induces a… Expand
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