FAQ

RASGRF1 wt Allele

Known as: RAS-GRF1, GNRP, Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 wt Allele 
Human RASGRF1 wild type allele is located in the vicinity of 15q24 and is approximately 129 kb in length. This allele, which encodes guanine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2009
01219902009

Related topics

Related topics

8 relations
15q24G2-M Cell Cycle CheckpointHomo sapiensMemory
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Broader (1)

RASGRF1 gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
RASGRF1 wt Allele
Signal Transduction
Homo sapiens
Ras Protein Specific Guanine Nucleotide Releasing Factor 1
Sonic Hedgehog Pathway
15q24

Papers overview

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2009
2009
Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) controls activation of extracellular signal-regulated kinase (ERK) signaling in the striatum and long-term behavioral responses to cocaine.
BACKGROUND Ras-extracellular signal-regulated kinase (Ras-ERK) signaling is central to the molecular machinery underlying… (More)
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Highly Cited
2006
Highly Cited
2006
Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.
NMDA-type glutamate receptors (NMDARs) contribute to many forms of long-term potentiation (LTP) and long-term depression (LTD… (More)
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2005
2005
Cell Divisions in the Drosophila Embryonic Mesoderm Are Repressed via Posttranscriptional Regulation of string/cdc25 by HOW
BACKGROUND Cell-cycle progression is tightly regulated during embryonic development. In the Drosophila early embryo, the levels… (More)
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2001
2001
Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).
Previous results have suggested that the Ras signaling pathway is involved in learning and memory. Ras is activated by nucleotide… (More)
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1997
1997
Identification of a dominant-negative mutation in the yeast CDC25 guanine nucleotide exchange factor for Ras
In previous studies we changed five conserved amino acid residues in the catalytic domain of the yeast Ras-specific guanine… (More)
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1996
1996
The kinetics of the B cyclin p56cdc13 and the phosphatase p80cdc25 during the cell cycle of the fission yeast Schizosaccharomyces pombe.
The levels of the B cyclin p56cdc13 and the phosphatase p80cdc25 have been followed in selection-synchronised cultures of… (More)
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1994
1994
Two subclasses of guanine exchange factor (GEF) domains revealed by comparison of activities of chimeric genes constructed from CDC25, SDC25 and BUD5 in Saccharomyces cerevisiae
Guanine Exchange Factor (GEF) activity for Ras proteins has been associated with a conserved domain in Cdc25p, Sdc25p in… (More)
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1993
1993
Saccharomyces cerevisiae CDC25 (1028-1589) is a guanine nucleotide releasing factor for mammalian ras proteins and is oncogenic in NIH3T3 cells.
The best characterized yeast guanine nucleotide releasing factor is CDC25, which acts on RAS and thereby stimulates cAMP… (More)
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1993
1993
Identification of a human guanine nucleotide-releasing factor (H-GRF55) specific for Ras proteins.
A critical step in the activation of cellular Ras is the release of bound GDP. Oligonucleotide primers derived from a mouse cDNA… (More)
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1990
1990
The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, addition of glucose to cells grown under glucose-derepressed conditions induces a… (More)
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