RAD 001

Known as: 001, RAD, RAD001 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE We investigated the global gene expression in a large panel of pancreatic endocrine tumors (PETs) aimed at identifying… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Cross-talk between the estrogen receptor (ER) and the phosphoinositide-3-kinase (PI3K)/Akt/mammalian target of rapamycin… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Evaluate the activity of everolimus (RAD001) in combination with octreotide long-acting repeatable (LAR) in patients with… (More)
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Highly Cited
2008
Highly Cited
2008
Numerous studies have established a causal link between aberrant mammalian target of rapamycin (mTOR) activation and… (More)
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Highly Cited
2008
Highly Cited
2008
Tuberous sclerosis (TSC) is a hamartoma syndrome attributable to mutations in either TSC1 or TSC2 in which brain involvement… (More)
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Highly Cited
2007
Highly Cited
2007
Rapamycin and several analogs, such as CCI-779 and RAD001, are currently undergoing clinical evaluation as anticancer agents. In… (More)
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Highly Cited
2006
Highly Cited
2006
Stimulation of the insulin and insulin-like growth factor I (IGF-I) receptor activates the phosphoinositide-3-kinase/Akt/mTOR… (More)
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Highly Cited
2006
Highly Cited
2006
The PIK3CA gene, coding for the catalytic subunit p110alpha of class IA phosphatidylinositol 3-kinases (PI3Ks), is frequently… (More)
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Highly Cited
2005
Highly Cited
2005
Although DNA damaging agents have revolutionized chemotherapy against solid tumors, a narrow therapeutic window combined with… (More)
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Review
2003
Review
2003
The mammalian target of rapamycin (mTOR), an atypical serine/threonine kinase, plays a central role in the regulation of cell… (More)
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