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RAC3 gene

Known as: RAC3, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, Ras-Related C3 Botulinum Toxin Substrate 3 (Rho Family, Small GTP Binding Protein Rac3) Gene 
This gene is involved in both cytoskeletal remodeling and GTPase activity.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Surface ExtensionsCytoskeletal ModelingGTP BindingHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Rac3, but not Rac1, promotes ox‐LDL induced endothelial dysfunction by downregulating autophagy
The endothelial dysfunction induced by oxidized low‐density lipoprotein (ox‐LDL) plays an important role in the pathogenesis of… 
2018
2018
The inflammatory cytokine TNF contributes with RAC3-induced malignant transformation
RAC3 is a coactivator of steroid receptors and NF-κB. It is usually overexpressed in several tumors, contributes to maintain… 
2017
2017
Study on the molecular mechanism of Rac3 on regulating autophagy in human lung cancer cells.
PURPOSE Rac3 plays an important role in regulating tumorigenesis. Autophagy plays a vital role in tumorigenesis and tumor… 
2011
2011
[RAC3 overexpression is a transforming and proliferative signal that contributes to tumoral development].
RAC3 has been firstly characterized as a nuclear receptor coactivator that is found in limited amounts in normal cells, but is… 
2009
2009
Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling
Rac1 and Rac3 are highly homologous regulatory proteins that belong to the small GTPases of the Rho family. Previously, we showed… 
2009
2009
The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases.
Rac1 and Rac2, which belong to the Rho subfamily of Ras-related GTPases, play an essential role in activation of gp91phox/Nox2… 
2005
2005
Expression of Rac3 in human brain tumors
2005
2005
Rac3-mediated transformation requires multiple effector pathways.
Our initial characterization of Rac3, a close relative of the small GTPase Rac1, established its ability to promote membrane… 
Highly Cited
2003
Highly Cited
2003
Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling.
Rac1, a Rho family GTPase, is a mediator of diverse cellular functions including membrane ruffling, cell cycle progression, and… 
1998
1998
Identification of a novel Rac3-interacting protein C1D.
Rac3 is a small GTPase of the Rho family, members of which have been implicated in tumorigenesis, cell growth/death and… 
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