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R411

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Radical Transfer in E . Coli Ribonucleotide Reductase : a NHY / RA-Mutant Unmasks a New Conformation of the Pathway Residue 731
2009
2009
Functional performance of silicified microcrystalline cellulose versus microcrystalline cellulose: a case study
Background: During the development of a tablet dosage form of an investigational compound, R411, several aspects were identified… 
2006
2006
Evaluation of the effect of multiple-dose administration of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist on the major CYP isoform activities in healthy volunteers.
2005
2005
Evaluation of the effect of multiple-dose administration of R411, a dual α4β1–α4β7 integrin antagonist on the major CYP isoform activities in healthy volunteers
R411 is a dual antagonist of α4β1–α4β7 integrins that targets the inflammatory process in respiratory airways. It has shown good… 
2004
2004
Pharmacokinetics, Safety, and Tolerability of R411, a Dual α4β1‐α4β7 Integrin Antagonist After Oral Administration at Single and Multiple Once‐Daily Ascending Doses in Healthy Volunteers
R411 is a dual α4β1‐α4β7 integrin antagonist under development for the treatment of chronic asthma. The objective of this study… 
2004
2004
Pharmacokinetics, safety, and tolerability of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist after oral administration at single and multiple once-daily ascending doses in healthy…
R411 is a dual alpha4beta1-alpha4beta7 integrin antagonist under development for the treatment of chronic asthma. The objective… 
2004
2004
Dual α4/β1–α4/β7 vs α4/β1 selective antagonism is required for attenuation of allergic inflammatory responses
2004
2004
Effect of R411, a dual α4/β1‐α4/β7 Integrin antagonist being developed for asthma, on the activities of the major drug metabolizing enzymes after oral administration in healthy subjects
2004
2004
Selective modulation of inflammatory responses without immunosuppression with the dual α4/β1-α4/β7 integrin antagonist R411 in vivo☆
1998
1998
R411 Systemes vasopresseurs et hemorragie peranesthesie
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