R 848

Known as: R-848, R848 compound 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Newborns are prone to microbial infection and have poor memory responses to multiple antigens. We have previously shown that… (More)
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Highly Cited
2005
Highly Cited
2005
TLRs are involved in innate cell activation by conserved structures expressed by microorganisms. Human T cells express the mRNA… (More)
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Highly Cited
2005
Highly Cited
2005
TLR ligands that mimic pathogen associated molecular patterns and activate immune cells via Toll-like receptors (TLRs) are being… (More)
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Highly Cited
2004
Highly Cited
2004
Newborns are at increased risk of overwhelming infection, yet the mechanisms underlying this susceptibility are incompletely… (More)
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Highly Cited
2003
Highly Cited
2003
Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine) acts as synthetic adjuvant in anti-tumor responses. Here we first demonstrate… (More)
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Highly Cited
2002
Highly Cited
2002
The imidazoquinoline compounds imiquimod and R-848 are low-molecular-weight immune response modifiers that can induce the… (More)
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Highly Cited
2002
2000
2000
Imiquimod and R-848 are members of a family of immune response modifiers that stimulate cytokine production in monocyte… (More)
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Highly Cited
2000
Highly Cited
2000
R-848 and imiquimod belong to a class of immune response modifiers that are potent inducers of cytokines, including IFN-alpha… (More)
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Highly Cited
1999
Highly Cited
1999
Cytokines produced by antigen-presenting cells are known to affect the development and cytokine profile of T cells. The immune… (More)
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