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R 848

Known as: R-848, R848 compound 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

resiquimod

Papers overview

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2016
2016
Intestinal tuft cell function
tumor models. Exercise triggers the release of epinephrine, which enhances the mobilization and tumor infiltration of NK cells… 
2012
2012
Autocrine TNF Is Critical for the Survival of Human Dendritic Cells by Regulating BAK, BCL-2, and FLIPL
The life span of dendritic cells (DCs) is determined by the balance of pro- and antiapoptotic proteins. In this study, we report… 
2011
2011
The innate antiviral immune system of the cat: Molecular tools for the measurement of its state of activation
2010
2010
Reciprocal Regulation of Activating and Inhibitory Fcγ Receptors by TLR7/8 Activation: Implications for Tumor Immunotherapy
Purpose: Activation of Toll-like receptors (TLR) 7 and 8 by engineered agonists has been shown to aid in combating viruses and… 
2008
2008
TLR7/8 Ligand, R‐848, Inhibits IgE Synthesis by Acting Directly on B Lymphocytes
TLRs are involved in the regulation of immune responses. R‐848, a TLR7/8 ligand, has potent anti‐viral and anti‐tumour properties… 
Highly Cited
2007
Highly Cited
2007
Additive effects of CpG ODN and R-848 as adjuvants on augmenting immune responses to HBsAg vaccination.
2006
2006
Treatment of intravaginal HSV-2 infection in mice: a comparison of CpG oligodeoxynucleotides and resiquimod (R-848).
Highly Cited
2003
Highly Cited
2003
The novel synthetic immune response modifier R-848 (Resiquimod) shifts human allergen-specific CD4+ TH2 lymphocytes into IFN-gamma-producing cells.
BACKGROUND In experimental models, imidazoquinolines exhibit several immunomodulatory activities via Toll-like receptor signaling… 
2002
2002
Safety, pharmacokinetics, and pharmacodynamics of single doses of an oral p38 MAP kinase inhibitor (BIRB 796 BS) in healthy human males a placebo-controlled, randomised study, double blinded at each…
2001
2001
Clearance of Infection with Mycobacterium bovis BCG in Mice Is Enhanced by Treatment with S28463 (R-848), and Its Efficiency Depends on Expression of Wild-Type Nramp1 (Resistance Allele)
ABSTRACT The mouse bcg host resistance gene is known to control the activation of host macrophages for killing of intracellular… 
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